1,3-Bis(furan-2-ylmethyl)urea

Base Information

• Chemical Name: 1,3-Bis(furan-2-ylmethyl)urea
• CAS No.: 39200-98-1
• Molecular Formula: C₁₁H₁₂N₂O₃
• Molecular Weight: 220.228
• NSC Number: 166445
• DSSTox Substance ID: DTXSID10304602
• Wikidata: Q82050627
• ChEMBL ID: CHEMBL5015135
• Mol file: 39200-98-1.mol

Synonyms:1,3-bis(furan-2-ylmethyl)urea;39200-98-1;1,3-DIFURFURYLUREA;N,N'-bis(furan-2-ylmethyl)urea;NSC166445;CHEMBL5015135;SCHEMBL24575916;DTXSID10304602;AKOS003537094;NSC-166445;Z195662442

Chemical Property of 1,3-Bis(furan-2-ylmethyl)urea

Chemical Property:

• Vapor Pressure: 3.62E-08mmHg at 25°C
• Boiling Point: 446.5°C at 760 mmHg
• Flash Point: 223.8°C
• Density: 1.224g/cm³
• XLogP3: 0.6
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 220.08479225
• Heavy Atom Count: 16
• Complexity: 213

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=COC(=C1)CNC(=O)NCC2=CC=CO2

Technology Process of 1,3-Bis(furan-2-ylmethyl)urea

There total 12 articles about 1,3-Bis(furan-2-ylmethyl)urea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

furan-2-ylmethanamine (617-89-0) + carbon monoxide (201230-82-2) → N,N'-bis(furan-2-ylmethyl)urea (39200-98-1)

Guidance literature:

With C₆₂H₅₂AgAu₄N₂O₄P₄⁽³⁺⁾*3F₆Sb^(1-); In tetrahydrofuran; at 60 ℃; for 24h; under 3750.38 Torr; Inert atmosphere;

DOI:10.1002/anie.201603200

Reference yield: 91.0%

tetrachloromethane (56-23-5) + furan-2-ylmethanamine (617-89-0) → N,N'-bis(furan-2-ylmethyl)urea (39200-98-1)

Guidance literature:

With titanium(IV) oxide; caesium carbonate; for 10h; Irradiation;

Reference yield: 88.7%

furan-2-ylmethanamine (617-89-0) + trimethylsilyl diethylcarbamate (18279-61-3) → N,N'-bis(furan-2-ylmethyl)urea (39200-98-1)

Guidance literature:

In benzene; Reflux; Inert atmosphere;

DOI:10.1134/S1070363214060103

upstream raw materials:

furfural

urea

phosgene

furan-2-ylmethanamine