N-((3s,5s,7s)-adamantan-1-yl)-2-bromoacetamide

Base Information

Chemical Name:N-((3s,5s,7s)-adamantan-1-yl)-2-bromoacetamide
CAS No.:54059-81-3
Molecular Formula:C₁₂H₁₈BrNO
Molecular Weight:272.185
Hs Code.:

Synonyms:

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N-((3s,5s,7s)-adamantan-1-yl)-2-bromoacetamide

Chemical Property:

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Technology Process of N-((3s,5s,7s)-adamantan-1-yl)-2-bromoacetamide

There total 1 articles about N-((3s,5s,7s)-adamantan-1-yl)-2-bromoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 22118-09-8
2-bromoacetyl chloride

: 768-94-5
1-Adamantanamine

: 5689-59-8
N-(1-adamantyl)-2-chloroacetamide

: 54059-81-3
N-((3s,5s,7s)-adamantan-1-yl)-2-bromoacetamide

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; Overall yield = 58 %;
DOI:10.1021/acs.jmedchem.7b00485

Reference yield: 63.0%

: 25364-47-0
1-(2,6-diisopropylphenyl)-1H-imidazole

: 54059-81-3
N-((3s,5s,7s)-adamantan-1-yl)-2-bromoacetamide

: 1265918-96-4
1-(2,6-diisopropylphenyl)-3-[2-(1-adamantylamino)-2-oxoethyl]-1H-imidazol-3-ium bromide

Guidance literature:: In acetonitrile; at 84 ℃; for 12h; Reflux;
DOI:10.1002/adsc.201000592

Reference yield:

: 420-04-2
CYANAMID

: 51908-29-3
4-isothiocyanatobenzene sulfonamide

: 54059-81-3
N-((3s,5s,7s)-adamantan-1-yl)-2-bromoacetamide

: C₂₀H₂₅N₅O₃S₂

Guidance literature:: CYANAMID; 4-isothiocyanatobenzene sulfonamide; With potassium tert-butylate; In tetrahydrofuran; at 20 ℃; for 0.25h;

N-((3s,5s,7s)-adamantan-1-yl)-2-bromoacetamide; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/jm301234k