3-(4-Fluorophenyl)-2-methyl-4(3H)-pyrimidinone

Base Information

Chemical Name:3-(4-Fluorophenyl)-2-methyl-4(3H)-pyrimidinone
CAS No.:87356-53-4
Molecular Formula:C₁₁H₉FN₂O
Molecular Weight:204.204
Hs Code.:2933599090
DSSTox Substance ID:DTXSID901007498
Wikidata:Q83003539
Mol file:87356-53-4.mol

Synonyms:87356-53-4;BRN 4419682;3-(4-Fluorophenyl)-2-methyl-4(3H)-pyrimidinone;3-(4-Fluorophenyl)-2-methylpyrimidin-4(3H)-one;4(3H)-Pyrimidinone, 3-(4-fluorophenyl)-2-methyl-;DTXSID901007498;LS-135933

Suppliers and Price of 3-(4-Fluorophenyl)-2-methyl-4(3H)-pyrimidinone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-(4-Fluorophenyl)-2-methyl-4(3H)-pyrimidinone

Chemical Property:

Vapor Pressure:0.000317mmHg at 25°C
Boiling Point:320.5°C at 760 mmHg
PKA:-0.43±0.68(Predicted)
Flash Point:147.6°C
PSA：34.89000
Density:1.21g/cm³
LogP:1.68000
XLogP3:1.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:204.06989108
Heavy Atom Count:15
Complexity:317

Purity/Quality:: 99%+ ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=NC=CC(=O)N1C2=CC=C(C=C2)F

Technology Process of 3-(4-Fluorophenyl)-2-methyl-4(3H)-pyrimidinone

There total 2 articles about 3-(4-Fluorophenyl)-2-methyl-4(3H)-pyrimidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 67007-00-5
N'-(p-fluorophenyl)acetamidine

: 623-47-2
propynoic acid ethyl ester

: 87356-53-4
3-(4-Fluoro-phenyl)-2-methyl-3H-pyrimidin-4-one

Guidance literature:: In ethanol; at 35 ℃; for 24h;

Reference yield:

: 371-40-4
4-fluoroaniline

: 87356-53-4
3-(4-Fluoro-phenyl)-2-methyl-3H-pyrimidin-4-one

Guidance literature:: Multi-step reaction with 2 steps

1: 37 percent / AlCl₃

2: 67 percent / ethanol / 24 h / 35 °C

With aluminium trichloride; In ethanol;