3-deoxy-D-glycero-L-altro-nonulosonic acid

Base Information

• Chemical Name: 3-deoxy-D-glycero-L-altro-nonulosonic acid
• CAS No.: 145295-41-6
• Molecular Formula: C₉H₁₆O₉
• Molecular Weight: 268.221
• Mol file: 145295-41-6.mol

Synonyms:

Chemical Property of 3-deoxy-D-glycero-L-altro-nonulosonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-deoxy-D-glycero-L-altro-nonulosonic acid

There total 2 articles about 3-deoxy-D-glycero-L-altro-nonulosonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

D-talose (2595-98-4) + sodium pyruvate (113-24-6) → 3-deoxy-D-glycero-L-altro-nonulosonic acid (145295-41-6)

Guidance literature:

With potassium phosphate buffer; diothiothreitol; In water; at 37 ℃; for 72h; pH 7.4, sialic acid aldolase (EC 4.1.3.3, from Escherichia coli);

DOI:10.1021/ja00052a008

Reference yield:

D-Mannose (530-26-7) + Oxalacetic acid (328-42-7) → 3-deoxy-D-glycero-L-altro-nonulosonic acid (145295-41-6)

Guidance literature:

With sodium hydroxide; Dowex-50(H⁺) resin; nickel dichloride; Yield given. Multistep reaction;

DOI:10.1248/cpb.39.3140

Reference yield:

benzyl bromide (100-39-0) + 3-deoxy-D-glycero-L-altro-nonulosonic acid (145295-41-6) → (2S,4S,5R,6R)-2,4,5-Trihydroxy-6-((1S,2R)-1,2,3-trihydroxy-propyl)-tetrahydro-pyran-2-carboxylic acid benzyl ester

Guidance literature:

With caesium carbonate; Multistep reaction; 1.) H₂O, RT, 2.) DMF, 18 h;

DOI:10.1248/cpb.39.3140

upstream raw materials:

D-Mannose

Oxalacetic acid

D-talose

sodium pyruvate