Technology Process of cis methyl 3-(2,3-dimethoxyanilino)acrylate
There total 5 articles about cis methyl 3-(2,3-dimethoxyanilino)acrylate which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1) nBuLi, N,N,N',N'tetramethylethylenediamine; 2) trimethylsilylmethyl azide / 1) ether, hexane, 22 degC, 18.5 h.; 2) ether, hexane, 22 degC, 3.5 h.
2: 73 percent / methanol / 72 h / 22 °C
With
n-butyllithium; N,N,N,N,-tetramethylethylenediamine; trimethylsilylmethyl azide;
In
methanol;
DOI:10.1016/S0040-4020(01)96655-4
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1) nBuLi, N,N,N',N'tetramethylethylenediamine; 2) trimethylsilylmethyl azide / 1) ether, hexane, 22 degC, 18.5 h.; 2) ether, hexane, 22 degC, 3.5 h.
2: 24.9 g / methanol / 72 h / 22 °C
With
n-butyllithium; N,N,N,N,-tetramethylethylenediamine; trimethylsilylmethyl azide;
In
methanol;
DOI:10.1016/S0040-4020(01)96655-4
