Imidazo[2,1-f][1,6]naphthyridine, 2-[(1S,2S)-2-(5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazin-2-yl)cyclopropyl]-3-methyl-

Base Information

Chemical Name:Imidazo[2,1-f][1,6]naphthyridine, 2-[(1S,2S)-2-(5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazin-2-yl)cyclopropyl]-3-methyl-
CAS No.:1516896-06-2
Molecular Formula:C₂₁H₁₉N₇
Molecular Weight:369.429
Hs Code.:
Mol file:1516896-06-2.mol

Synonyms:

Suppliers and Price of Imidazo[2,1-f][1,6]naphthyridine, 2-[(1S,2S)-2-(5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazin-2-yl)cyclopropyl]-3-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 3 raw suppliers

Chemical Property of Imidazo[2,1-f][1,6]naphthyridine, 2-[(1S,2S)-2-(5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazin-2-yl)cyclopropyl]-3-methyl-

Chemical Property:

PKA:5.38±0.50(Predicted)
Density:1.52±0.1 g/cm3(Predicted)

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Imidazo[2,1-f][1,6]naphthyridine, 2-[(1S,2S)-2-(5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazin-2-yl)cyclopropyl]-3-methyl-

There total 12 articles about Imidazo[2,1-f][1,6]naphthyridine, 2-[(1S,2S)-2-(5,8-dimethyl[1,2,4]triazolo[1,5-a]pyrazin-2-yl)cyclopropyl]-3-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1516895-53-6
trans-2-(2-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)cyclopropyl)-3-methylimidazo[2,1-f][1,6]naphthyridine

: 1516896-09-5,1516895-53-6
3-methyl-2-((1S,2S)-2-(quinolin-2-yl)cyclopropyl)-3H-imidazo[4,5-f]quinoline

: 1516896-06-2
C₂₁H₁₉N₇

Guidance literature:: With isopropylamine; In methanol; acetonitrile; Resolution of racemate;

Reference yield:

: trans-1-(2-(5,8-dimethyl-[1,2,4]triazolo[1,5-a]pyrazin-2-yl)cyclopropyl)propan-1-one

: 1516896-09-5,1516895-53-6
3-methyl-2-((1S,2S)-2-(quinolin-2-yl)cyclopropyl)-3H-imidazo[4,5-f]quinoline

: 1516896-06-2
C₂₁H₁₉N₇

Guidance literature:: Multi-step reaction with 3 steps

1: phenyltrimethylammonium tribromide / tetrahydrofuran / 40 °C

2: sodium hydrogencarbonate / ethanol / 80 °C

3: isopropylamine / acetonitrile; methanol / Resolution of racemate

With phenyltrimethylammonium tribromide; sodium hydrogencarbonate; isopropylamine; In tetrahydrofuran; methanol; ethanol; acetonitrile;

Reference yield:

: 23616-32-2
5-chloro-[1,6]naphthyridine

: 1516896-09-5,1516895-53-6
3-methyl-2-((1S,2S)-2-(quinolin-2-yl)cyclopropyl)-3H-imidazo[4,5-f]quinoline

: 1516896-06-2
C₂₁H₁₉N₇

Guidance literature:: Multi-step reaction with 4 steps

1: sodium azide / N,N-dimethyl-formamide / 80 °C

2: hydrogenchloride; tin(ll) chloride / methanol / 60 °C

3: sodium hydrogencarbonate / ethanol / 80 °C

4: isopropylamine / acetonitrile; methanol / Resolution of racemate

With hydrogenchloride; sodium azide; sodium hydrogencarbonate; isopropylamine; tin(ll) chloride; In methanol; ethanol; N,N-dimethyl-formamide; acetonitrile;