1H-Benzimidazole,1,5,6-trimethyl-(9CI)

Base Information

• Chemical Name: 1H-Benzimidazole,1,5,6-trimethyl-(9CI)
• CAS No.: 1128-27-4
• Molecular Formula: C10H12N2
• Molecular Weight: 160.219
• Hs Code.: 2933990090
• Mol file: 1128-27-4.mol

Synonyms:1,5,6-trimethyl-4-aminobenzimidazole;1,5,6-trimethyl-1H-benzoimidazole;1,5,6-trimethyl-1H-benzoimidazol-4-ylamine;1,5,6-Trimethyl-1H-benzimidazol;1,5,6-trimethyl-benzimidazole;

Chemical Property of 1H-Benzimidazole,1,5,6-trimethyl-(9CI)

Chemical Property:

• Melting Point: 142-143 °C(Solv: ethyl acetate (141-78-6); ligroine (8032-32-4))
• Boiling Point: 298.1±43.0 °C(Predicted)
• PKA: 5.98±0.10(Predicted)
• PSA: 17.82000
• Density: 1.07±0.1 g/cm3(Predicted)
• LogP: 2.19010

Purity/Quality:

98%,99%, ^*data from raw suppliers

1,5,6-TRIMETHYL-1H-BENZIMIDAZOLE 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• General Description: 1H-Benzimidazole,1,5,6-trimethyl-(9CI) (also known as 1,5,6-trimethyl-1H-benzoimidazole) is a substituted benzimidazole derivative that has been utilized as a ligand in organometallic chemistry, particularly in the formation of homodinuclear and heterodinuclear complexes with rhodium(I) and iridium(I). It coordinates to metal centers through its nitrogen and carbon atoms, contributing to the structural and electronic properties of the resulting complexes. Additionally, it has been studied in cobalt(III) complexes, where its coordination behavior and trans influence on metal-ligand bonds have been characterized, demonstrating its relevance in coordination chemistry and structural analysis.

Technology Process of 1H-Benzimidazole,1,5,6-trimethyl-(9CI)

There total 22 articles about 1H-Benzimidazole,1,5,6-trimethyl-(9CI) which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

5,6-dimethyl-1H-benzo[d]imida-zole (582-60-5) + methyl iodide (74-88-4) → 1,5,6-trimethylbenzimidazole (1128-27-4)

Guidance literature:

With potassium hydroxide; 18-crown-6 ether; In tetrachloromethane; for 30h; Ambient temperature;

Reference yield: 94.0%

carbon dioxide (124-38-9,18923-20-1) + N1,4,5-trimethylbenzene-1,2-diamine (17978-55-1) → 1,5,6-trimethylbenzimidazole (1128-27-4)

Guidance literature:

With tris(pentafluorophenyl)borate; phenylsilane; In tetrahydrofuran; at 120 ℃; for 24h; under 7500.75 Torr; Autoclave;

DOI:10.1021/acs.orglett.6b03030

Reference yield: 78.0%

methanol (67-56-1) + 4,5-dimethyl-1,2-phenylenediamine (3171-45-7) → 1,5,6-trimethylbenzimidazole (1128-27-4)

Guidance literature:

With [Mn(HN(C₂H₄PⁱPr₂)₂)(CO)₂Br]; sodium carbonate; at 165 ℃; for 16h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1002/cjoc.202100886

upstream raw materials:

formic acid

N¹,4,5-trimethylbenzene-1,2-diamine

5,6-dimethyl-1H-benzo[d]imida-zole

methyl iodide

Downstream raw materials:

1,5,6-trimethylbenzimidazole-4,7-dione

1,5,6-Trimethyl-1H-benzoimidazole-4,7-diamine

(2-{[(3E)-5-amino-2,2-dimethylfuran-3(2H)-ylidene]amino}-4,5-dimethylphenyl)methylformamide

(2-{[(4E)-2-amino-1-oxaspiro[4.5]dec-2-en-4-ylidene]amino}-4,5-dimethylphenyl)methylformamide