Acetamide, 2-(hydroxyimino)-N-(3-methylphenyl)-

Base Information

• Chemical Name: Acetamide, 2-(hydroxyimino)-N-(3-methylphenyl)-
• CAS No.: 1132-29-2
• Molecular Formula: C9H10N2O2
• Molecular Weight: 178.191
• DSSTox Substance ID: DTXSID00425239
• Mol file: 1132-29-2.mol

Synonyms:2-hydroxyimino-N-(3-methylphenyl)acetamide;Acetamide, 2-(hydroxyimino)-N-(3-methylphenyl)-;1132-29-2;DTXSID00425239

Chemical Property of Acetamide, 2-(hydroxyimino)-N-(3-methylphenyl)-

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 2
• Exact Mass: 178.074227566
• Heavy Atom Count: 13
• Complexity: 204

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=CC=C1)NC(=O)C=NO

Technology Process of Acetamide, 2-(hydroxyimino)-N-(3-methylphenyl)-

There total 3 articles about Acetamide, 2-(hydroxyimino)-N-(3-methylphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

chloral ethyl hemiacetal (515-83-3) + 1-amino-3-methylbenzene (108-44-1) → 2-hydroxyimino-N-m-tolylacetamide (1132-29-2)

Guidance literature:

With hydrogenchloride; hydroxylamine hydrochloride; sodium sulfate; In ethanol; water; at 80 ℃; for 3h;

DOI:10.1080/00304940409355374

Reference yield: 53.0%

chloral hydrate (302-17-0) + 1-amino-3-methylbenzene (108-44-1) → 2-hydroxyimino-N-m-tolylacetamide (1132-29-2)

Guidance literature:

With hydroxylamine hydrochloride; In hydrogenchloride; for 0.0333333h; Heating;

DOI:10.1016/0040-4020(80)80221-3

Reference yield: 50.0%

chloral (75-87-6) + 1-amino-3-methylbenzene (108-44-1) → 2-hydroxyimino-N-m-tolylacetamide (1132-29-2)

Guidance literature:

With hydroxylamine hydrochloride;

upstream raw materials:

chloral hydrate

1-amino-3-methylbenzene

chloral

chloral ethyl hemiacetal

Downstream raw materials:

6-methylindoline-2,3-dione

4-methyl-1H-indole-2,3-dione

2,3-dihydro-7-methyl-5H-as-triazino[5,6-b]indole-3-thione

7-methylquinoline-4-carboxylic acid