4-Methyl-2-<methyl>phenol

Base Information

• Chemical Name: 4-Methyl-2-<methyl>phenol
• CAS No.: 155454-61-8
• Molecular Formula: C₁₅H₁₈N₂O
• Molecular Weight: 242.321
• Mol file: 155454-61-8.mol

Synonyms:

Chemical Property of 4-Methyl-2-<methyl>phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-Methyl-2-<methyl>phenol

There total 1 articles about 4-Methyl-2-<methyl>phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

formaldehyd (50-00-0,30525-89-4,61233-19-0) + p-cresol (106-44-5) + N-methyl-2-pyridinemethanamine (21035-59-6) → 4-Methyl-2-<methyl>phenol (155454-61-8) + 2,6-Bis<methyl>-4-methylphenol

Guidance literature:

Yield given. Multistep reaction; 1.) 80 deg C, 1 h, 2.) i-PrOH, reflux, 2 d;

DOI:10.1021/jo00087a046

Reference yield: 30.0%

1-methyl-piperazine (109-01-3) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-Methyl-2-<methyl>phenol (155454-61-8) → 4-Methyl-6-<(4-methylpiperazin-1-yl)methyl>-2-<methyl>phenol

Guidance literature:

In ethanol; for 19h; Heating;

DOI:10.1021/jo00087a046

Reference yield:

pyrrolidine (123-75-1) + formaldehyd (50-00-0,30525-89-4,61233-19-0) + 4-Methyl-2-<methyl>phenol (155454-61-8) → 4-Methyl-2-<methyl>-6-(pyrrolidin-1-ylmethyl)phenol

Guidance literature:

Yield given. Multistep reaction; 1.) 80 deg C, 1 h, 2.) i-PrOH, reflux, 20 h;

DOI:10.1021/jo00087a046

upstream raw materials:

formaldehyd

p-cresol

N-methyl-2-pyridinemethanamine