Cyclohexanone, 2-methyl-6-(phenylmethylene)-, (E)-

Base Information

• Chemical Name: Cyclohexanone, 2-methyl-6-(phenylmethylene)-, (E)-
• CAS No.: 1208-47-5
• Molecular Formula: C14H16O
• Molecular Weight: 200.28
• Hs Code.: 2914399090
• Mol file: 1208-47-5.mol

Synonyms:.trans-2-Benzyliden-6-methyl-cyclohexanon;.trans-6-Benzyliden-2-methyl-cyclohexanon;.(+/-)-1-methyl-3-(benzylidene-(t))-cyclohexanone-(2);2-methyl-6-benzylidene cyclohexanone;.(+/-)-1-Methyl-3-(benzyliden-(t))-cyclohexanon-(2);.2-methyl-6-benzylidene-cyclohexanone;

Chemical Property of Cyclohexanone, 2-methyl-6-(phenylmethylene)-, (E)-

Chemical Property:

• PSA: 17.07000
• LogP: 3.45910

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of Cyclohexanone, 2-methyl-6-(phenylmethylene)-, (E)-

There total 14 articles about Cyclohexanone, 2-methyl-6-(phenylmethylene)-, (E)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

benzaldehyde (100-52-7) + 2-Methylcyclohexanone (583-60-8) → (E)-2-benzylidene-6-methylcyclohexanone (1208-47-5)

Guidance literature:

With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; for 3h; Ambient temperature;

DOI:10.1246/bcsj.64.3384

Reference yield: 52.0%

benzaldehyde (100-52-7) + 2-Methylcyclohexanone (583-60-8) → 6-benzylidene-2-methylcyclohexan-1-one (1208-47-5,1450-67-5,54146-11-1,6324-75-0)

Guidance literature:

With potassium fluoride; tetramethylorthosilicate; In N,N-dimethyl-formamide; at 70 ℃; for 5h;

DOI:10.1055/s-1983-30309

Reference yield: 51.0%

methanol (67-56-1) + 2-Benzylidenecyclohexanone (5682-83-7) → 6-benzylidene-2-methylcyclohexan-1-one (1208-47-5,1450-67-5,54146-11-1,6324-75-0)

Guidance literature:

With [(N,N′-bis(diisopropylphosphino)-2,6-diaminopyridine)Mn(CO)₃][Br]; sodium t-butanolate; In toluene; at 120 ℃; for 20h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1039/c8cc08064j

upstream raw materials:

sodium ethanolate

benzaldehyde

2-Methylcyclohexanone

6-methyl-1-trimethylsiloxycyclohex-1-ene

Downstream raw materials:

2-benzyl-6-methylcyclohexan-1-one

2-benzyl-6-methyl-cyclohex-2-enone

6-Benzyl-2-methyl-cyclohex-2-en-1-on

4-hydroxy-3-<α-(3-methyl-2-oxocyclohexyl)benzyl>coumarin