N,N,9-trimethyl-9H-purin-6-amine

Base Information

• Chemical Name: N,N,9-trimethyl-9H-purin-6-amine
• CAS No.: 3013-82-9
• Molecular Formula: C8H11 N5
• Molecular Weight: 177.209
• Mol file: 3013-82-9.mol

Synonyms:Adenine,N,N,9-trimethyl- (7CI,8CI); Adenine, N6,N6,9-trimethyl- (6CI);6,6,9-Trimethyladenine; 6-Dimethylamino-9-methyl-9H-purine;N,N,9-Trimethyladenine; NSC 4949

Chemical Property of N,N,9-trimethyl-9H-purin-6-amine

Chemical Property:

• Vapor Pressure: 0.000104mmHg at 25°C
• Boiling Point: 337.5°C at 760 mmHg
• Flash Point: 157.9°C
• Density: 1.28g/cm³

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N,9-trimethyl-9H-purin-6-amine

There total 11 articles about N,N,9-trimethyl-9H-purin-6-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

dimethyl amine (124-40-3) + 9-methyl-6-(1,2,4-triazol-4-yl)purine (158782-61-7) → 6-N,N-dimethyl-9-methyladenine (3013-82-9)

Guidance literature:

In water; for 1h; Ambient temperature;

DOI:10.1021/ja00099a061

Reference yield: 80.0%

5-amino-4-(N,N-dimethylamidino)-1-methylimidazole cyanide + N,N-dimethylformamide diethyl diacetal (1188-33-6) → 6-N,N-dimethyl-9-methyladenine (3013-82-9)

Guidance literature:

In acetonitrile; at 0 - 20 ℃; for 5h;

DOI:10.1002/ejoc.200700416

Reference yield: 26.0%

6-Dimethylaminopurine (938-55-6) + methyl iodide (74-88-4) → 6-N,N-dimethyl-9-methyladenine (3013-82-9)

Guidance literature:

With sodium methylate; In dimethyl sulfoxide; for 1h; Ambient temperature;

DOI:10.1021/jm00398a019

upstream raw materials:

6-chloro-9-methyl-9H-purine

dimethyl amine

6-Dimethylaminopurine

methyl iodide

Downstream raw materials:

N,N,N',N'-tetramethyl-para-semiquinonediimine

9-methylpurine

9-methylhypoxanthine