4-(Benzyloxy)-3,5-difluorobenzaldehyde

Base Information

Chemical Name:4-(Benzyloxy)-3,5-difluorobenzaldehyde
CAS No.:125036-88-6
Molecular Formula:C₁₄H₁₀F₂O₂
Molecular Weight:248.229
Hs Code.:
DSSTox Substance ID:DTXSID70577259
Wikidata:Q82467215
Mol file:125036-88-6.mol

Synonyms:4-(Benzyloxy)-3,5-difluorobenzaldehyde;125036-88-6;3,5-Difluoro-4-(phenylmethoxy)-benzaldehyde;3,5-difluoro-4-phenylmethoxybenzaldehyde;4-benzyloxy-3,5-difluorobenzaldehyde;4-benzyloxy-3,5-difluoro-benzaldehyde;SCHEMBL2301807;DTXSID70577259;QKRBYGWUSGMSLG-UHFFFAOYSA-N;MFCD12025065;AKOS016007737;AS-33350;3,5-Difluoro-4-(Phenylmethoxy)benzaldehyde;CS-0195315;Benzaldehyde, 3,5-difluoro-4-(phenylmethoxy)-;A890320

Suppliers and Price of 4-(Benzyloxy)-3,5-difluorobenzaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
3,5-Difluoro-4-(Phenylmethoxy)-Benzaldehyde
500mg
$ 330.00

Crysdot
4-(Benzyloxy)-3,5-difluorobenzaldehyde 97%
5g
$ 506.00

AOBChem
3,5-Difluoro-4-(phenylmethoxy)-benzaldehyde 95%
1g
$ 193.00

American Custom Chemicals Corporation
4-(BENZYLOXY)-3,5-DIFLUOROBENZALDEHYDE 95.00%
5MG
$ 497.94

Alichem
4-(Benzyloxy)-3,5-difluorobenzaldehyde
5g
$ 980.00

Alichem
4-(Benzyloxy)-3,5-difluorobenzaldehyde
1g
$ 323.01

Total 11 raw suppliers

Chemical Property of 4-(Benzyloxy)-3,5-difluorobenzaldehyde

Chemical Property:

PSA：26.30000
LogP:3.35630
Storage Temp.:2-8°C
XLogP3:3.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:4
Exact Mass:248.06488588
Heavy Atom Count:18
Complexity:255

Purity/Quality:

97% ^*data from raw suppliers

3,5-Difluoro-4-(Phenylmethoxy)-Benzaldehyde ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)COC2=C(C=C(C=C2F)C=O)F

Technology Process of 4-(Benzyloxy)-3,5-difluorobenzaldehyde

There total 4 articles about 4-(Benzyloxy)-3,5-difluorobenzaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 100-39-0
benzyl bromide

: 118276-06-5
3,5-difluoro-4-hydroxybenzaldehyde

: 125036-88-6
4-(benzyloxy)-3,5-difluorobenzaldehyde

Guidance literature:: With potassium carbonate; In N,N-dimethyl-formamide; at 60 ℃; for 2h; Inert atmosphere;
DOI:10.1002/cbic.201400033

Reference yield:

: 100-44-7
benzyl chloride

: 118276-06-5
3,5-difluoro-4-hydroxybenzaldehyde

: 125036-88-6
4-(benzyloxy)-3,5-difluorobenzaldehyde

Guidance literature:: With potassium carbonate; In water; dimethyl sulfoxide;

Reference yield:

: 99045-18-8
1-Bromo-3,5-difluoro-4-(benzyloxy)benzene

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 125036-88-6
4-(benzyloxy)-3,5-difluorobenzaldehyde

: 947279-23-4
3-(benzyloxy)-2,4-difluorobenzaldehyde

Guidance literature:: 1-Bromo-3,5-difluoro-4-(benzyloxy)benzene; With n-butyllithium; In tetrahydrofuran; at -78 ℃; for 1h; Inert atmosphere;

N,N-dimethyl-formamide; In tetrahydrofuran; at -78 ℃; for 1h;