methyl 4-methoxy-1-naphthoate

Base Information

• Chemical Name: methyl 4-methoxy-1-naphthoate
• CAS No.: 13041-64-0
• Molecular Formula: C13H12O3
• Molecular Weight: 216.236
• Mol file: 13041-64-0.mol

Synonyms:1-Methoxy-4-methoxycarbonyl-naphthalin;1-Naphthalenecarboxylic acid,4-methoxy-,methyl ester;4-Methoxy-1-naphthoesaeure-methylester;methyl 4-methoxy-1-naphthoate;methyl ester of 4-methoxy-1-naphthalenecarboxylic acid;

Chemical Property of methyl 4-methoxy-1-naphthoate

Chemical Property:

• PSA: 35.53000
• LogP: 2.63500

Purity/Quality:

95% ^*data from raw suppliers

Methyl4-methoxy-1-naphthoate ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of methyl 4-methoxy-1-naphthoate

There total 6 articles about methyl 4-methoxy-1-naphthoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.3%

4-methoxy-1-naphthoic acid (13041-62-8) → methyl ester of 4-methoxy-1-naphthalenecarboxylic acid (13041-64-0)

Guidance literature:

With sulfuric acid; In methanol; at 0 - 70 ℃;

DOI:10.1002/cjoc.202000342

Reference yield: 85.0%

4-methoxy-1-naphthoic acid (13041-62-8) + methyl iodide (74-88-4) → methyl ester of 4-methoxy-1-naphthalenecarboxylic acid (13041-64-0)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; at 25 ℃; for 3h;

DOI:10.1002/anie.201905485

Reference yield: 30.0%

methanol (67-56-1) + tetranitromethane (509-14-8) + 1-Methoxynaphthalene (2216-69-5) → 1-methoxy-4-nitronaphthalene (4900-63-4) + 2-nitro-1-methoxynaphthalene (4900-62-3) + methyl ester of 4-methoxy-1-naphthalenecarboxylic acid (13041-64-0)

Guidance literature:

In dichloromethane; at 25 ℃; for 16h; Yields of byproduct given; Irradiation;

upstream raw materials:

methanol

tetranitromethane

1-Methoxynaphthalene

diazomethane

Downstream raw materials:

2-(4-methoxynaphthalene-1-carbonyl)acetonitrile