p-methylbenzaldehyde oxime benzoyl ester

Base Information

• Chemical Name: p-methylbenzaldehyde oxime benzoyl ester
• CAS No.: 16061-97-5
• Molecular Formula: C₁₅H₁₃NO₂
• Molecular Weight: 239.274
• Mol file: 16061-97-5.mol

Synonyms:

Chemical Property of p-methylbenzaldehyde oxime benzoyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-methylbenzaldehyde oxime benzoyl ester

There total 2 articles about p-methylbenzaldehyde oxime benzoyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

p-methylbenzaldehyde oxime (3717-15-5) + benzoyl chloride (98-88-4) → p-methylbenzaldehyde oxime benzoyl ester (16061-97-5,18802-69-2)

Guidance literature:

With pyridine;

DOI:10.1021/ja01850a017

Reference yield:

4-methyl-benzaldehyde (104-87-0) → p-methylbenzaldehyde oxime benzoyl ester (16061-97-5,18802-69-2)

Guidance literature:

Multi-step reaction with 2 steps

1: hydroxylamine hydrochloride; sodium hydroxide / water; methanol / 20 °C

2: triethylamine / dichloromethane / 20 °C

With hydroxylamine hydrochloride; triethylamine; sodium hydroxide; In methanol; dichloromethane; water;

DOI:10.1039/c7cc04965j

Reference yield: 87.0%

7-methoxy-2-naphthol (5060-82-2) + p-methylbenzaldehyde oxime benzoyl ester (16061-97-5,18802-69-2) → 8-methoxy-2-(p-tolyl)naphtho[1,2-d]oxazole

Guidance literature:

With iron(III) chloride; oxygen; In toluene; at 20 ℃; under 760.051 Torr; regioselective reaction; Schlenk technique;

DOI:10.1039/c7cc04965j

upstream raw materials:

p-methylbenzaldehyde oxime

benzoyl chloride

4-methyl-benzaldehyde

Downstream raw materials:

para-methylbenzonitrile

2-(4-methylphenyl)naphtho[1,2-d][1,3]oxazole