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4-((Tert-butyldimethylsilyloxy)methyl)aniline

Base Information
  • Chemical Name:4-((Tert-butyldimethylsilyloxy)methyl)aniline
  • CAS No.:131230-76-7
  • Molecular Formula:C13H23NOSi
  • Molecular Weight:237.417
  • Hs Code.:
  • DSSTox Substance ID:DTXSID00454347
  • Nikkaji Number:J978.849B
  • Wikidata:Q82275824
  • Mol file:131230-76-7.mol
4-((Tert-butyldimethylsilyloxy)methyl)aniline

Synonyms:131230-76-7;4-((tert-butyldimethylsilyloxy)methyl)aniline;4-[(tert-ButyldiMethylsilyloxy)Methyl]aniline;Benzenamine, 4-[[[(1,1-dimethylethyl)dimethylsilyl]oxy]methyl]-;4-[[tert-butyl(dimethyl)silyl]oxymethyl]aniline;4-aminobenzyloxy-tert-butyldimethylsilane;4-[[(tert-Butyldimethylsilyl)oxy]methyl]aniline;4-(tert-butyldimethylsilyloxymethyl)aniline;4-(((tert-Butyldimethylsilyl)oxy)methyl)aniline;4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]benzenamine;4-{[(tert-butyldimethylsilyl)oxy]methyl}aniline;SCHEMBL133816;DTXSID00454347;WYUUHAORVPRPFB-UHFFFAOYSA-N;MFCD20483304;AKOS025403461;4-(t-butyldimethylsilyloxymethyl)aniline;DS-10030;CS-0009163;C72246;4-((tert-butyldimethylsilyloxy)methyl)benzenamine;A926829

Suppliers and Price of 4-((Tert-butyldimethylsilyloxy)methyl)aniline
Supply Marketing:
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]benzenamine
  • 1g
  • $ 165.00
  • Matrix Scientific
  • 4-((tert-Butyldimethylsilyloxy)methyl)aniline 97%
  • 5g
  • $ 900.00
  • Matrix Scientific
  • 4-((tert-Butyldimethylsilyloxy)methyl)aniline 97%
  • 10g
  • $ 1365.00
  • Crysdot
  • 4-((tert-Butyldimethylsilyloxy)methyl)aniline 95%
  • 5g
  • $ 475.00
  • Chemenu
  • 4-[[(tert-Butyldimethylsilyl)oxy]methyl]aniline 95%
  • 5g
  • $ 449.00
  • Chemenu
  • 4-[[(tert-Butyldimethylsilyl)oxy]methyl]aniline 95%
  • 1g
  • $ 153.00
  • Ambeed
  • 4-((tert-Butyldimethylsilyloxy)methyl)aniline 95%
  • 10g
  • $ 905.00
  • Ambeed
  • 4-((tert-Butyldimethylsilyloxy)methyl)aniline 95%
  • 5g
  • $ 548.00
  • Ambeed
  • 4-((tert-Butyldimethylsilyloxy)methyl)aniline 95%
  • 250mg
  • $ 69.00
  • Ambeed
  • 4-((tert-Butyldimethylsilyloxy)methyl)aniline 95%
  • 100mg
  • $ 41.00
Total 18 raw suppliers
Chemical Property of 4-((Tert-butyldimethylsilyloxy)methyl)aniline
Chemical Property:
  • Boiling Point:305.0±17.0 °C(Predicted) 
  • PKA:4.32±0.10(Predicted) 
  • PSA:35.25000 
  • Density:0.952±0.06 g/cm3(Predicted) 
  • LogP:4.37180 
  • Storage Temp.:under inert gas (nitrogen or Argon) at 2–8 °C 
  • Hydrogen Bond Donor Count:1
  • Hydrogen Bond Acceptor Count:2
  • Rotatable Bond Count:4
  • Exact Mass:237.154890892
  • Heavy Atom Count:16
  • Complexity:215
Purity/Quality:

97% *data from raw suppliers

4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]benzenamine *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes: 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:CC(C)(C)[Si](C)(C)OCC1=CC=C(C=C1)N
  • Uses 4-[[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]benzenamine is used in the synthesis of immunomodulatory agents.
Technology Process of 4-((Tert-butyldimethylsilyloxy)methyl)aniline

There total 9 articles about 4-((Tert-butyldimethylsilyloxy)methyl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With hydrogen; 5percent Pd/C; In tetrahydrofuran; at 20 ℃;
DOI:10.1021/ja993959z
Guidance literature:
With 1H-imidazole; In dichloromethane; at 20 ℃; for 24h;
DOI:10.1039/d1cc05217a
Guidance literature:
With ammonium iodide; hydrazine; In ethanol; at 70 ℃; for 48h;
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