5-Bromo-2,4-diethoxypyrimidine

Base Information

• Chemical Name: 5-Bromo-2,4-diethoxypyrimidine
• CAS No.: 132164-47-7
• Molecular Formula: C8H11BrN2O2
• Molecular Weight: 247.08900
• Hs Code.: 2933599090
• DSSTox Substance ID: DTXSID20563920
• Nikkaji Number: J2.403.391K
• Wikidata: Q82448438
• Mol file: 132164-47-7.mol

Synonyms:5-Bromo-2,4-diethoxypyrimidine;132164-47-7;Pyrimidine, 5-bromo-2,4-diethoxy-;SCHEMBL2723864;DTXSID20563920;ZCDUGAGUVHOMPG-UHFFFAOYSA-N;MFCD20441928;5-bromo-2,4-bis(ethyloxy)pyrimidine;SB58352;BS-20664;CS-0204372

Chemical Property of 5-Bromo-2,4-diethoxypyrimidine

Chemical Property:

• PSA: 44.24000
• LogP: 2.03650
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 4
• Exact Mass: 246.00039
• Heavy Atom Count: 13
• Complexity: 148

Purity/Quality:

98%min ^*data from raw suppliers

5-Bromo-2,4-diethoxypyrimidine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCOC1=NC(=NC=C1Br)OCC

Technology Process of 5-Bromo-2,4-diethoxypyrimidine

There total 4 articles about 5-Bromo-2,4-diethoxypyrimidine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

sodium ethanolate (141-52-6) → 2,4-diethoxy-5-bromopyrimidine (132164-47-7)

Guidance literature:

DOI:10.1021/ja01294a010

Reference yield:

sodium ethanolate (141-52-6) → 2,4-diethoxy-5-bromopyrimidine (132164-47-7)

Guidance literature:

DOI:10.1021/ja01294a010

Reference yield:

2,4-dichloro-5-bromopyrimidine (36082-50-5) + sodium ethanolate (141-52-6) → 2,4-diethoxy-5-bromopyrimidine (132164-47-7)

Guidance literature:

DOI:10.1021/ja01316a041

upstream raw materials:

2,4-dichloro-5-bromopyrimidine

sodium ethanolate

ethanol