Oxiranemethanamine, N,N-dimethyl-

Base Information

• Chemical Name: Oxiranemethanamine, N,N-dimethyl-
• CAS No.: 13222-40-7
• Molecular Formula: C5H11NO
• Molecular Weight: 101.148
• European Community (EC) Number: 863-455-1
• DSSTox Substance ID: DTXSID80444589
• Nikkaji Number: J35.186E
• Mol file: 13222-40-7.mol

Synonyms:13222-40-7;Oxiranemethanamine, N,N-dimethyl-;1-dimethylamino-2,3-epoxypropane;N,N-dimethyl-1-(oxiran-2-yl)methanamine;dimethyl[(oxiran-2-yl)methyl]amine;N,N-Dimethyl-1-oxiran-2-ylmethanamine;SCHEMBL933250;DTXSID80444589;N,N-Dimethyl-2-oxiranemethanamine;MFCD09740456;N-(Oxiranylmethyl)-N,N-dimethylamine;AKOS000145898

Chemical Property of Oxiranemethanamine, N,N-dimethyl-

Chemical Property:

• XLogP3: 0
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 2
• Exact Mass: 101.084063974
• Heavy Atom Count: 7
• Complexity: 63.1

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)CC1CO1

Technology Process of Oxiranemethanamine, N,N-dimethyl-

There total 4 articles about Oxiranemethanamine, N,N-dimethyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

3-(dimethylamino)-1,2-propanediol (623-57-4) → 1-dimethylamino-2,3-epoxypropane (13222-40-7)

Guidance literature:

With ethyl azodicarboxylate; triphenylphosphine;

DOI:10.1080/15257779508012452

Reference yield:

N,N-dimethyl-2-propen-1-amine (2155-94-4) → 1-dimethylamino-2,3-epoxypropane (13222-40-7)

Guidance literature:

N,N-dimethyl-2-propen-1-amine; With 2-Picolinic acid; manganese(II) triflate; acetonitrile boron trifluoride complex; at -78 ℃; for 0.166667h;

at -78 ℃; for 0.5h; Reagent/catalyst; Temperature;

DOI:10.1021/acs.orglett.6b00518

Reference yield:

dimethyl amine (124-40-3) + epichlorohydrin (106-89-8,24969-06-0,13403-37-7) → 1-dimethylamino-2,3-epoxypropane (13222-40-7)

Guidance literature:

With diethyl ether;

upstream raw materials:

dimethyl amine

epichlorohydrin

3-(dimethylamino)-1,2-propanediol

N,N-dimethyl-2-propen-1-amine

Downstream raw materials:

5-dimethylaminomethyl-3-phenylcarbamoyl-2-iminooxazolidine

5-dimethylaminomethyl-3-phenylcarbamoyl-2-oxazolidinone

1,3-bis-(dimethylamino)propan-2-ol