Technology Process of Oxiranecarboxylic acid, 3-cyclohexyl-, methyl ester, (2R,3S)-
There total 4 articles about Oxiranecarboxylic acid, 3-cyclohexyl-, methyl ester, (2R,3S)- which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1-ethyl-3-(dimethylaminopropyl)carbodiimide hydrochloride / dimethylformamide / 12 h / 20 °C
2.1: La-(S)-BINOL-Ph3AsO complex; 4 Angstroem molecular sieves; tert-butyl hydroperoxide / toluene; tetrahydrofuran / 4 h / 20 °C
2.2: tetrahydrofuran; toluene / 20 °C
With
tert.-butylhydroperoxide; La-(S)-BINOL-Ph3AsO; 4 A molecular sieve; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; N,N-dimethyl-formamide; toluene;
DOI:10.1016/j.tet.2003.06.010
- Guidance literature:
-
1-[(2E)-3-cyclohexyl-1-oxo-2-propenyl]-4-phenyl-1H-imidazole;
With
tert.-butylhydroperoxide; La-(S)-BINOL-Ph3AsO; 4 A molecular sieve;
In
tetrahydrofuran; toluene;
at 20 ℃;
for 4h;
methanol;
In
tetrahydrofuran; toluene;
at 20 ℃;
Title compound not separated from byproducts;
DOI:10.1016/j.tet.2003.06.010
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 2) RuO4
2: CsF / dimethylformamide
With
ruthenium tetroxide; cesium fluoride;
In
N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)74855-6
