Technology Process of C29H26N4O2S
There total 3 articles about C29H26N4O2S which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
1-(((1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methyl)-3-((1S,2S)-2-(pyrrolidin-1-yl)cyclohexyl)thiourea;
In
tert-butyl methyl ether;
at 0 ℃;
Overall yield = 86 %; enantioselective reaction;
DOI:10.1039/c3cc38386e
- Guidance literature:
-
Multi-step reaction with 3 steps
1: acetic acid / 20 °C
2: acetic acid; sodium acetate / Reflux
3: 1-(((1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methyl)-3-((1S,2S)-2-(pyrrolidin-1-yl)cyclohexyl)thiourea / tert-butyl methyl ether / 0 °C
With
1-(((1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methyl)-3-((1S,2S)-2-(pyrrolidin-1-yl)cyclohexyl)thiourea; sodium acetate; acetic acid;
In
tert-butyl methyl ether;
DOI:10.1039/c3cc38386e
- Guidance literature:
-
Multi-step reaction with 2 steps
1: acetic acid; sodium acetate / Reflux
2: 1-(((1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methyl)-3-((1S,2S)-2-(pyrrolidin-1-yl)cyclohexyl)thiourea / tert-butyl methyl ether / 0 °C
With
1-(((1R,4aS,10aR)-7-isopropyl-1,4a-dimethyl-1,2,3,4,4a,9,10,10a-octahydrophenanthren-1-yl)methyl)-3-((1S,2S)-2-(pyrrolidin-1-yl)cyclohexyl)thiourea; sodium acetate; acetic acid;
In
tert-butyl methyl ether;
DOI:10.1039/c3cc38386e