N,N-Diethyl-2-naphthamide

Base Information

• Chemical Name: N,N-Diethyl-2-naphthamide
• CAS No.: 13577-84-9
• Molecular Formula: C15H17NO
• Molecular Weight: 227.306
• Hs Code.: 2924299090
• Mol file: 13577-84-9.mol

Synonyms:2-Naphthamide,N,N-diethyl;N,N-diethyl-naphthalene-2-carboxamide;N,N-Diethyl-2-naphthamide;2-Naphthalenecarboxamide,N,N-diethyl;

Chemical Property of N,N-Diethyl-2-naphthamide

Chemical Property:

• PSA: 20.31000
• LogP: 3.32180

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of N,N-Diethyl-2-naphthamide

There total 21 articles about N,N-Diethyl-2-naphthamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

diethylamine (109-89-7) + naphthalene-2-carboxylate (93-09-4) → N,N-diethyl-2-naphthamide (13577-84-9)

Guidance literature:

diethylamine; With iodine; triphenylphosphine; In dichloromethane; at 0 ℃; Inert atmosphere;

naphthalene-2-carboxylate; In dichloromethane; at 0 ℃; Inert atmosphere;

With triethylamine; In dichloromethane; at 0 - 20 ℃; for 1h; Inert atmosphere;

DOI:10.1039/c5ra03184b

Reference yield: 98.0%

1-methoxynaphthalene-2-carboxylic acid diethylamide (404574-87-4) → N,N-diethyl-2-naphthamide (13577-84-9)

Guidance literature:

With triethylsilane; carbonyl bis(hydrido)tris(triphenylphosphine)ruthenium(II); In toluene; at 125 - 135 ℃; for 20h;

Reference yield: 98.0%

carbon monoxide (201230-82-2) + 2-iodonaphthalene (612-55-5) + triethylamine (121-44-8) → N,N-diethyl-2-naphthamide (13577-84-9)

Guidance literature:

With palladium 10% on activated carbon; oxygen; In acetonitrile; at 100 ℃; for 8h; under 4560.31 Torr; Autoclave; Green chemistry;

DOI:10.1021/acs.joc.5b02385

upstream raw materials:

naphthalene

N,N-diethylcarbamyl chloride

carbon monoxide

2-naphthyl triflate

Downstream raw materials:

ethyl-2-naphthoate

N,N-diethyl-3-(1-phenylethyl)-2-naphthamide

N-ethyl-N-(naphthalen-2-ylmethyl)ethanamine

β-naphthaldehyde