N,N-Dimethyl-4-phenyl-2-pyrimidinecarboxamide

Base Information

Chemical Name:N,N-Dimethyl-4-phenyl-2-pyrimidinecarboxamide
CAS No.:74647-41-9
Molecular Formula:C₁₃H₁₃N₃O
Molecular Weight:227.266
Hs Code.:
DSSTox Substance ID:DTXSID401253525

Synonyms:N,N-Dimethyl-4-phenyl-2-pyrimidinecarboxamide;DTXSID401253525;74647-41-9

Suppliers and Price of N,N-Dimethyl-4-phenyl-2-pyrimidinecarboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N,N-Dimethyl-4-phenyl-2-pyrimidinecarboxamide

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:227.105862047
Heavy Atom Count:17
Complexity:261

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN(C)C(=O)C1=NC=CC(=N1)C2=CC=CC=C2

Technology Process of N,N-Dimethyl-4-phenyl-2-pyrimidinecarboxamide

There total 4 articles about N,N-Dimethyl-4-phenyl-2-pyrimidinecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 65.0%

: 74647-40-8
methyl 6-phenylpyrimidine-2-carboxylate

: 124-40-3
dimethyl amine

: 74647-41-9
N,N-dimethyl-6-phenylpyrimidine-2-carboxamide

Guidance literature:: In methanol; water; for 10h; Ambient temperature;
DOI:10.1248/cpb.28.571

Reference yield: 14.0%

: 3438-48-0
4-phenylpyrimidine

: 68-12-2,33513-42-7
N,N-dimethyl-formamide

: 74647-41-9
N,N-dimethyl-6-phenylpyrimidine-2-carboxamide

: 74503-00-7
N,N-dimethyl-6-phenylpyrimidine-4-carboxamide

Guidance literature:: With tert.-butylhydroperoxide; iron(II) sulfate; In water; at 10 - 20 ℃; for 1h;
DOI:10.1248/cpb.28.571

Reference yield:

: 74647-39-5
6-phenylpyrimidine-2-carboxylic acid

: 74647-41-9
N,N-dimethyl-6-phenylpyrimidine-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: 99 percent / thionyl chloride / 10 h / Ambient temperature

2: 65 percent / methanol; H₂O / 10 h / Ambient temperature

With thionyl chloride; In methanol; water;
DOI:10.1248/cpb.28.571