Methyl 4-phenylpyrimidine-2-carboxylate

Base Information

Chemical Name:Methyl 4-phenylpyrimidine-2-carboxylate
CAS No.:74647-40-8
Molecular Formula:C₁₂H₁₀N₂O₂
Molecular Weight:214.224
Hs Code.:
DSSTox Substance ID:DTXSID101281159

Synonyms:methyl 4-phenylpyrimidine-2-carboxylate;74647-40-8;Methyl 4-phenylpyrimidin-2-carboxylate;MFCD18417752;Methyl4-Phenylpyrimidine-2-carboxylate;methyl 4-phenyl-2-pyrimidinecarboxylate;DTXSID101281159;AC6733;AKOS025213269;SY059685;A915632

Suppliers and Price of Methyl 4-phenylpyrimidine-2-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Alichem
Methyl4-phenylpyrimidine-2-carboxylate
250mg
$ 611.46

AK Scientific
Methyl4-phenylpyrimidine-2-carboxylate
1g
$ 937.00

Total 2 raw suppliers

Chemical Property of Methyl 4-phenylpyrimidine-2-carboxylate

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:3
Exact Mass:214.074227566
Heavy Atom Count:16
Complexity:239

Purity/Quality:

97% ^*data from raw suppliers

Methyl4-phenylpyrimidine-2-carboxylate ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=NC=CC(=N1)C2=CC=CC=C2

Technology Process of Methyl 4-phenylpyrimidine-2-carboxylate

There total 2 articles about Methyl 4-phenylpyrimidine-2-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 67-56-1
methanol

: 74647-39-5
6-phenylpyrimidine-2-carboxylic acid

: 74647-40-8
methyl 6-phenylpyrimidine-2-carboxylate

Guidance literature:: With thionyl chloride; for 10h; Ambient temperature;
DOI:10.1248/cpb.28.571

Reference yield:

: 21203-79-2
2-methyl-6-phenylpyrimidine

: 74647-40-8
methyl 6-phenylpyrimidine-2-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: 57 percent / SeO₂ / pyridine / 5 h / Heating

2: 99 percent / thionyl chloride / 10 h / Ambient temperature

With selenium(IV) oxide; thionyl chloride; In pyridine;
DOI:10.1248/cpb.28.571