1,2-Bis(chloro(phenyl)methylene)hydrazine

Base Information

• Chemical Name: 1,2-Bis(chloro(phenyl)methylene)hydrazine
• CAS No.: 729-44-2
• Molecular Formula: C₁₄H₁₀Cl₂N₂
• Molecular Weight: 277.153
• DSSTox Substance ID: DTXSID601197309
• Mol file: 729-44-2.mol

Synonyms:N-(chloro(phenyl)methylene)benzohydrazonoyl chloride;SAZIGIAVMOYTBU-UHFFFAOYSA-N;DTXSID601197309;1,2-bis(chloro(phenyl)methylene)hydrazine;N-(Chlorophenylmethylene)benzenecarbohydrazonoyl chloride

Chemical Property of 1,2-Bis(chloro(phenyl)methylene)hydrazine

Chemical Property:

• Melting Point: 120-122 °C
• Boiling Point: 390.4±25.0 °C(Predicted)
• PKA: 0.18±0.50(Predicted)
• Density: 1.21±0.1 g/cm3(Predicted)
• XLogP3: 5.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 3
• Exact Mass: 276.0221037
• Heavy Atom Count: 18
• Complexity: 282

Purity/Quality:

99% ^*data from raw suppliers

N'-(Chloro(phenyl)methylene)benzohydrazonoylchloride 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: C1=CC=C(C=C1)C(=NN=C(C2=CC=CC=C2)Cl)Cl

Technology Process of 1,2-Bis(chloro(phenyl)methylene)hydrazine

There total 25 articles about 1,2-Bis(chloro(phenyl)methylene)hydrazine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

N'-benzoylbenzohydrazide (787-84-8) → 1,2-bis[chloro(phenyl)methylidene]hydrazone (729-44-2,116377-04-9)

Guidance literature:

With phosphorus pentachloride; In toluene; at 120 ℃; for 6h; Inert atmosphere;

Reference yield: 75.0%

benzaldehyde benzylidenehydrazone (28867-76-7) → 1,2-bis[chloro(phenyl)methylidene]hydrazone (729-44-2,116377-04-9)

Guidance literature:

With chlorine; In acetic acid; Ambient temperature;

Reference yield: 48.0%

cyclohexane (110-82-7,25012-93-5) + 3-Chlor-3-phenyl-1,2-diaziridin (74670-99-8) → 1,2-bis[chloro(phenyl)methylidene]hydrazone (729-44-2,116377-04-9) + (chloro-cyclohexyl-methyl)benzene (28047-23-6) + 1,2-dichloro-1,2-diphenylethylene (13700-82-8)

Guidance literature:

In benzene; at 23 ℃; Kinetics; Irradiation; activation parameters was determined;

DOI:10.1016/S0040-4039(98)02196-0

upstream raw materials:

N'-benzoylbenzohydrazide

benzaldehyde benzylidenehydrazone

acetone

3-chloro-3-phenyl-3H-diazirine

Downstream raw materials:

2,5-bis-(phenyl)-1,3,4-oxadiazole

bis-(α-ethoxy-benzylidene)-hydrazine

benzophenone azine

diphenyl-[1,3,4]thiadiazole