1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol

Base Information

Chemical Name:1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol
CAS No.:26495-07-8
Molecular Formula:C14H12 N2 O S
Molecular Weight:256.328
Hs Code.:2933990090
DSSTox Substance ID:DTXSID80397384
Nikkaji Number:J3.574.138K
Wikidata:Q82198673
ChEMBL ID:CHEMBL1579950
Mol file:26495-07-8.mol

Synonyms:26495-07-8;1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol;1-(4-methoxyphenyl)-1h-benzo[d]imidazole-2-thiol;3-(4-methoxyphenyl)-1H-benzimidazole-2-thione;1-(4-methoxyphenyl)-1H-1,3-benzodiazole-2-thiol;MLS000536081;CHEMBL1579950;SCHEMBL10353247;DTXSID80397384;HMS2372J11;BBA49507;AKOS000116403;SMR000155420;EN300-03316;J3.574.138K;AB00447731-04;3-(4-Methoxyphenyl)-1H-benzoimidazole-2(3H)-thione;Z56828922;1-(4-Methoxyphenyl)-1,3-dihydro-2H-benzimidazole-2-thione;Benzenepropanoic acid, 3-fluoro-.beta.-oxo-, ethyl ester;2H-Benzimidazole-2-thione, 1,3-dihydro-1-(4-methoxyphenyl)-

Suppliers and Price of 1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
1-(4-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-2-THIOL 95.00%
5G
$ 1114.58

American Custom Chemicals Corporation
1-(4-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-2-THIOL 95.00%
2.5G
$ 932.60

American Custom Chemicals Corporation
1-(4-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-2-THIOL 95.00%
1G
$ 692.46

AK Scientific
1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol
2.5g
$ 664.00

AK Scientific
1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol
1g
$ 387.00

AK Scientific
1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol
250mg
$ 203.00

Total 3 raw suppliers

Chemical Property of 1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol

Chemical Property:

Vapor Pressure:2.57E-07mmHg at 25°C
Boiling Point:421.6°C at 760 mmHg
Flash Point:208.8°C
PSA：65.85000
Density:1.35g/cm³
LogP:3.32280
XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:2
Exact Mass:256.06703418
Heavy Atom Count:18
Complexity:315

Purity/Quality:

99% ^*data from raw suppliers

1-(4-METHOXY-PHENYL)-1H-BENZOIMIDAZOLE-2-THIOL 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:COC1=CC=C(C=C1)N2C3=CC=CC=C3NC2=S

Technology Process of 1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol

There total 8 articles about 1-(4-Methoxy-phenyl)-1H-benzoimidazole-2-thiol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 75-15-0,12122-00-8
carbon disulfide

: C₃₁H₂₇N₂OP

: 26495-07-8
1-(4-methoxyphenyl)-2,3-dihydro-1H-1,3-benzodiazole-2-thione

Guidance literature:: In N,N-dimethyl-formamide; at 20 ℃; for 24h;
DOI:10.1055/s-0035-1560639

Reference yield: 88.0%

: 25914-22-1
N-(4-methoxyphenyl)benzene-1,2-diamine

: 6160-65-2
1,1'-Thiocarbonyldiimidazole

: 26495-07-8
1-(4-methoxyphenyl)-2,3-dihydro-1H-1,3-benzodiazole-2-thione

Guidance literature:: In dichloromethane; at 0 ℃; for 0.5h;
DOI:10.1021/ml200125r

Reference yield:

: 104-94-9
4-methoxy-aniline

: 26495-07-8
1-(4-methoxyphenyl)-2,3-dihydro-1H-1,3-benzodiazole-2-thione

Guidance literature:: Multi-step reaction with 3 steps

1: triethylamine / 1 h / 150 °C / Microwave irradiation

2: palladium 10% on activated carbon; hydrogen / methanol / 3 h / 2068.65 Torr

3: dichloromethane / 0.5 h / 0 °C

With palladium 10% on activated carbon; hydrogen; triethylamine; In methanol; dichloromethane;
DOI:10.1021/ml200125r