difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane

Base Information

• Chemical Name: difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane
• CAS No.: 438201-92-4
• Molecular Formula: C₁₉H₃₂F₂Ge
• Molecular Weight: 371.05
• Mol file: 438201-92-4.mol

Synonyms:

Chemical Property of difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane

There total 3 articles about difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane (438201-91-3) + hydrogen fluoride (7664-39-3,12381-92-9,32057-09-3,74835-82-8) → difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane (438201-92-4)

Guidance literature:

In water; benzene; HF in H2O was added to soln. of Ge-complex in benzene, reflux for 1 h under N2 or Ar; sepd., aq. layer was extd. with Et2O, dried over Na2SO4, solvent was removed in vacuo, crystd. from pentane; elem. anal.;

DOI:10.1016/S0022-328X(01)01223-2

Reference yield:

trichloro(2,4,6-triisopropylphenyl)germane (190080-50-3) → difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane (438201-92-4)

Guidance literature:

Multi-step reaction with 2 steps

1: MeI / pentane

2: water; benzene

With MeI; In water; pentane; benzene;

DOI:10.1016/S0022-328X(01)01223-2

Reference yield:

2,4,6-triisopropyl-1-bromobenzene (21524-34-5) → difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane (438201-92-4)

Guidance literature:

Multi-step reaction with 2 steps

1: n-BuLi / tetrahydrofuran; hexane

2: water

With n-BuLi; In tetrahydrofuran; hexane; water;

DOI:10.1021/om100233y

upstream raw materials:

tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane

hydrogen fluoride

trichloro(2,4,6-triisopropylphenyl)germane

2,4,6-triisopropyl-1-bromobenzene

Downstream raw materials:

(2,4,6-triisopropylphenyl)(t-Bu)Ge(F)C(Cl)P(2,4,6-tri-tert-butylphenyl)

(2,4,6-tri-tert-butylphenyl)P=C(Cl)Ge(t-Bu)(F)(2,4,6-triisopropylphenyl)

1-(2,4,6-tri-tert-butylphenyl)-3-(2,4,6-triisopropylphenyl)-3-tert-butyl-1-arsa-3-germaallene

C₆H₂(CH(CH₃)2)3C(CH₃)3GeOCH₃CHAsC₆H₂(C(CH₃)3)3