tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane

Base Information

• Chemical Name: tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane
• CAS No.: 438201-91-3
• Molecular Formula: C₂₁H₃₈GeO₂
• Molecular Weight: 395.122
• Mol file: 438201-91-3.mol

Synonyms:

Chemical Property of tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane

There total 1 articles about tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

trichloro(2,4,6-triisopropylphenyl)germane (190080-50-3) + tert.-butyl lithium (594-19-4) → tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane (438201-91-3)

Guidance literature:

With MeI; In pentane; byproducts: LiI; t-BuLi in pentane was added slowly to soln. of Ge-compound in pentane, cooled to 0°C, refluxed for 1 h, cooled to room temp., MeI was added under N2 or Ar; filtered, crystd. from pentane; elem. anal.;

DOI:10.1016/S0022-328X(01)01223-2

Reference yield: 78.0%

tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane (438201-91-3) + hydrogen fluoride (7664-39-3,12381-92-9,32057-09-3,74835-82-8) → difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane (438201-92-4)

Guidance literature:

In water; benzene; HF in H2O was added to soln. of Ge-complex in benzene, reflux for 1 h under N2 or Ar; sepd., aq. layer was extd. with Et2O, dried over Na2SO4, solvent was removed in vacuo, crystd. from pentane; elem. anal.;

DOI:10.1016/S0022-328X(01)01223-2

Reference yield:

tert-butyl-2,4,6-triisopropylphenyl(dimethoxy)germane (438201-91-3) → 3-(2,4,6-triisopropylphenyl)-3-tert-butyl-1-(2,4,6-tri-tert-butylphenyl)germaphosphaallene (438201-89-9)

Guidance literature:

Multi-step reaction with 3 steps

1: water; benzene

2: t-BuLi / hexane; tetrahydrofuran

3: t-BuLi / pentane; diethyl ether

With t-BuLi; In tetrahydrofuran; diethyl ether; hexane; water; pentane; benzene;

DOI:10.1016/S0022-328X(01)01223-2

upstream raw materials:

trichloro(2,4,6-triisopropylphenyl)germane

tert.-butyl lithium

Downstream raw materials:

difluoro(2,4,6-triisopropylphenyl)(tert-butyl)germane

3-(2,4,6-triisopropylphenyl)-3-tert-butyl-1-(2,4,6-tri-tert-butylphenyl)germaphosphaallene

(C₃H₇)3C₆H₂GeOHC₄H₉CHP(C₄H₉)3C₆H₂

(2,4,6-triisopropylphenyl)(t-Bu)Ge(F)C(Cl)P(2,4,6-tri-tert-butylphenyl)