Tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate

Base Information

Chemical Name:Tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate
CAS No.:442126-36-5
Molecular Formula:C₁₂H₂₄N₂O₃
Molecular Weight:244.334
Hs Code.:
DSSTox Substance ID:DTXSID401190076
Mol file:442126-36-5.mol

Synonyms:442126-36-5;tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate;4-(2-Amino-ethoxy)-piperidine-1-carboxylic acid tert-butyl ester;tert-Butyl 4-(2-aminoethoxy)-piperidine-1-carboxylate;2-[(1-Boc-4-piperidyl)oxy]ethanamine;SCHEMBL21997805;DTXSID401190076;MFCD21092285;1-Boc-4-(2-aminoethoxy)-piperidine;AKOS017392188;AM100823;SY266741;EN300-73949;F8881-1985;1,1-Dimethylethyl 4-(2-aminoethoxy)-1-piperidinecarboxylate;4-(2-Aminoethoxy)piperidine-1-carboxylic acid tert-butyl ester

Suppliers and Price of Tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Matrix Scientific
tert-Butyl4-(2-aminoethoxy)-piperidine-1-carboxylate 95%
1g
$ 1064.00

Matrix Scientific
tert-Butyl4-(2-aminoethoxy)-piperidine-1-carboxylate 95%
5g
$ 3496.00

Matrix Scientific
tert-Butyl4-(2-aminoethoxy)-piperidine-1-carboxylate 95%
2.500g
$ 2321.00

AK Scientific
Tert-butyl4-(2-aminoethoxy)piperidine-1-carboxylate
5g
$ 1815.00

Activate Scientific
1-Boc-4-(2-aminoethoxy)-piperidine 97%
250 mg
$ 360.00

Acrotein
1-Boc-4-(2-aminoethoxy)-piperidine 97%
0.25g
$ 256.67

Total 3 raw suppliers

Chemical Property of Tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate

Chemical Property:

Boiling Point:344.8±32.0 °C(Predicted)
PKA:8.76±0.10(Predicted)
Density:1.06±0.1 g/cm3(Predicted)
XLogP3:0.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:244.17869263
Heavy Atom Count:17
Complexity:243

Purity/Quality:

99% ^*data from raw suppliers

tert-Butyl4-(2-aminoethoxy)-piperidine-1-carboxylate 95% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(C)OC(=O)N1CCC(CC1)OCCN

Technology Process of Tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate

There total 3 articles about Tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

: 857653-96-4
tert-butyl 4-(2-amino-2-oxoethoxy)piperidine-1-carboxylate

: 442126-36-5
tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate

Guidance literature:: With borane-THF; In tetrahydrofuran; at 70 ℃; for 12h; Inert atmosphere;

Reference yield:

: 189889-45-0
4-(ethoxycarbonylmethoxy)piperidine-1-carboxylic acid tert-butylester

: 442126-36-5
tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: ammonium hydroxide / methanol / 24 h / 65 °C / Inert atmosphere

2: borane-THF / tetrahydrofuran / 12 h / 70 °C / Inert atmosphere

With ammonium hydroxide; borane-THF; In tetrahydrofuran; methanol;

Reference yield:

: 109384-19-2
t-butyl 4-hydroxy piperidine-1-carboxylate

: 442126-36-5
tert-butyl 4-(2-aminoethoxy)piperidine-1-carboxylate

Guidance literature:: Multi-step reaction with 3 steps

1: dirhodium tetraacetate / dichloromethane / 48 h / 0 - 25 °C / Inert atmosphere

2: ammonium hydroxide / methanol / 24 h / 25 - 65 °C / Inert atmosphere

3: borane-THF / tetrahydrofuran / 12 h / 25 - 70 °C / Inert atmosphere

With dirhodium tetraacetate; ammonium hydroxide; borane-THF; In tetrahydrofuran; methanol; dichloromethane;