ETHYL ACETOACETATE SODIUM SALT

Base Information

• Chemical Name: ETHYL ACETOACETATE SODIUM SALT
• CAS No.: 20412-62-8
• Molecular Formula: C₆H₉O₃*Na
• Molecular Weight: 152.125
• Mol file: 20412-62-8.mol

Synonyms:

Chemical Property of ETHYL ACETOACETATE SODIUM SALT

Chemical Property:

• Melting Point: 168?°C (dec.)(lit.)
• Storage Temp.: Refrigerator (+4°C)

Purity/Quality:

98%,99%, ^*data from raw suppliers

Ethyl acetoacetate sodium salt ^*data from reagent suppliers

Safty Information:

• Hazard Codes: Xi:Irritant
• Statements: R36/38:Irritating to eyes and skin.
• Safety Statements: S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39:Wear suitable g

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of ETHYL ACETOACETATE SODIUM SALT

There total 1 articles about ETHYL ACETOACETATE SODIUM SALT which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

ethyl acetoacetate (141-97-9) → enolate sodique de l'acetylacetate d'ethyle (20412-62-8,66279-49-0)

Guidance literature:

With sodium hydride; In diethyl ether; paraffin oil; at 20 ℃; for 0.5h;

DOI:10.1002/ejoc.201403433

Reference yield: 80.0%

enolate sodique de l'acetylacetate d'ethyle (20412-62-8,66279-49-0) + α-bromoacetophenone (70-11-1) → ethyl 2-acetyl-4-oxo-4-phenylbutanoate (52313-46-9)

Guidance literature:

In toluene; for 24h;

Reference yield: 70.0%

allyl iodid (556-56-9) + enolate sodique de l'acetylacetate d'ethyle (20412-62-8,66279-49-0) → ethyl 3-oxohept-6-enoate (17605-06-0)

Guidance literature:

enolate sodique de l'acetylacetate d'ethyle; With n-butyllithium; In tetrahydrofuran; hexane; at 0 ℃;

allyl iodid; In tetrahydrofuran; hexane; at 20 ℃; for 1.5h;

DOI:10.1021/jo0514624

upstream raw materials:

ethyl acetoacetate

Downstream raw materials:

ethyl 2-acetyl-3,3-bis(methylthio)acrylate

ethyl (Z)-3-ethoxybut-2-enoate

ethyl 2-ethyl-3-oxobutanoate

ethyl 2-chloro-3-oxo-butyrate

Refernces