Azido-PEG6-CH2CO2t-butyl ester

Base Information

Chemical Name:Azido-PEG6-CH2CO2t-butyl ester
CAS No.:297162-49-3
Molecular Formula:C₁₈H₃₅N₃O₈
Molecular Weight:421.491
Hs Code.:
Mol file:297162-49-3.mol

Synonyms:

Suppliers and Price of Azido-PEG6-CH2CO2t-butyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

BroadPharm
Azido-PEG6-CH2CO2-t-Bu 98%
1 G
$ 1200.00

Apolloscientific
Azido-PEG6-CH2CO2t-butyl ester
250mg
$ 662.00

Activate Scientific
N3-PEG6-CH2COOtBu 95+%
1 g
$ 730.00

Acrotein
N3-PEG6-CH2COOtBu 97%
0.5g
$ 385.00

Total 15 raw suppliers

Chemical Property of Azido-PEG6-CH2CO2t-butyl ester

Chemical Property:

Purity/Quality:

98%,99%, ^*data from raw suppliers

Azido-PEG6-CH2CO2-t-Bu 98% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Description Azido-PEG6-CH2CO2-t-Bu contain an azide group and a t-butyl ester. PEG spacer increases reagent's solubility in aqueous media. The azide (N3) group can react with alkyne, BCN, DBCO via Click Chemistry. The t-butyl protected carboxyl group can be deprotected under acidic condition.

Technology Process of Azido-PEG6-CH2CO2t-butyl ester

There total 17 articles about Azido-PEG6-CH2CO2t-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 5292-43-3
bromoacetic acid tert-butyl ester

: 86770-69-6
17-azido-3,6,9,12,15-pentaoxaheptadecan-1-ol

: 297162-49-3
tert-butyl 20-azido-3,6,9,12,15,18-hexaoxaeicosanoate

Guidance literature:: With iron oxide; potassium iodide; In dichloromethane; at 20 ℃; for 120h;
DOI:10.1021/ja902743u

Reference yield: 33.0%

: tert-butyl 20-iodo-3,6,9,12,15,18-hexaoxicosanoate

: 297162-49-3
tert-butyl 20-azido-3,6,9,12,15,18-hexaoxaeicosanoate

Guidance literature:: With sodium azide; In N,N-dimethyl-formamide; at 50 ℃; for 2h;

Reference yield:

: 2615-15-8
pentaethylene glycol

: 297162-49-3
tert-butyl 20-azido-3,6,9,12,15,18-hexaoxaeicosanoate

Guidance literature:: Multi-step reaction with 3 steps

1.1: 49 percent / Ag₂O / CH₂Cl₂ / 48 h / 20 °C

2.1: 98 percent / NaN₃ / dimethylformamide / 2.5 h / 110 °C

3.1: NaH / tetrahydrofuran / 1.33 h / 0 - 20 °C

3.2: 87 percent / tetrahydrofuran / 15 h / Heating

With sodium azide; sodium hydride; silver(l) oxide; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/jm050893b