N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide

Base Information

Chemical Name:N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide
CAS No.:77903-26-5
Molecular Formula:C₁₂H₁₈N₂O₂
Molecular Weight:222.287
Hs Code.:
DSSTox Substance ID:DTXSID50507514
Wikidata:Q82363778

Synonyms:N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide;77903-26-5;N-(5-Methoxy-4-methylpyridin-3-yl)-2,2-dimethylpropanamide;SCHEMBL23169930;DTXSID50507514

Suppliers and Price of N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Crysdot
N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide 95+%
1g
$ 429.00

Chemenu
N-(5-methoxy-4-methylpyridin-3-yl)pivalamide 95%
1g
$ 405.00

Alichem
N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide
1g
$ 343.00

Total 2 raw suppliers

Chemical Property of N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide

Chemical Property:

XLogP3:1.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:3
Exact Mass:222.136827821
Heavy Atom Count:16
Complexity:248

Purity/Quality:

95+% ^*data from raw suppliers

N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide 95+% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC1=C(C=NC=C1NC(=O)C(C)(C)C)OC

Technology Process of N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide

There total 3 articles about N-(5-Methoxy-4-methylpyridin-3-yl)pivalamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 3282-30-2
pivaloyl chloride

: 77903-26-5
3-Methoxy-4-methyl-5-(pivaloylamino)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / Triethylamine / CHCl₃ / 0.08 h / ice temperature

2: n-BuLi/hexane / 1.) THF, -25 deg C, 1 h, 2.) THF, -70 deg C, 0.5 h

With n-butyllithium; hexane; triethylamine; In chloroform;
DOI:10.1021/jo00330a044

Reference yield:

: 64436-92-6
3-amino-5-methoxypyridine

: 77903-26-5
3-Methoxy-4-methyl-5-(pivaloylamino)pyridine

Guidance literature:: Multi-step reaction with 2 steps

1: 94 percent / Triethylamine / CHCl₃ / 0.08 h / ice temperature

2: n-BuLi/hexane / 1.) THF, -25 deg C, 1 h, 2.) THF, -70 deg C, 0.5 h

With n-butyllithium; hexane; triethylamine; In chloroform;
DOI:10.1021/jo00330a044

Reference yield:

: 77903-25-4
N-(5-methoxy-3-pyridyl)-2,2-dimethylpropanamide

: 74-88-4
methyl iodide

: 77903-26-5
3-Methoxy-4-methyl-5-(pivaloylamino)pyridine

Guidance literature:: With n-butyllithium; hexane; Yield given. Multistep reaction; 1.) THF, -25 deg C, 1 h, 2.) THF, -70 deg C, 0.5 h;
DOI:10.1021/jo00330a044