N-methylbiphenyl-2-amine

Base Information

• Chemical Name: N-methylbiphenyl-2-amine
• CAS No.: 14925-09-8
• Molecular Formula: C13H13N
• Molecular Weight: 183.253
• Hs Code.: 2921499090
• European Community (EC) Number: 811-642-3
• Nikkaji Number: J1.524.209D
• Mol file: 14925-09-8.mol

Synonyms:N-methylbiphenyl-2-amine;14925-09-8;N-methyl-2-phenylaniline;2-(N-Methylamino)-1,1'-biphenyl;[1,1'-Biphenyl]-2-amine, N-methyl-;N-methyl-[1,1'-biphenyl]-2-amine;Biphenyl-2-yl-methyl-amine;MFCD00179576;[1,1'-Biphenyl]amine, N-methyl-;methylaminobiphenyl;N-Methyl-o-phenylaniline;N-methyl-2-biphenylylamine;SCHEMBL1039296;CARILLOXVAEKID-UHFFFAOYSA-N;AKOS000251311;CS-W019420;GS-4211;SY045937;A3273;FT-0656072;EN300-58838

Chemical Property of N-methylbiphenyl-2-amine

Chemical Property:

• Vapor Pressure: 0mmHg at 25°C
• Boiling Point: 329.964oC at 760 mmHg
• PKA: 4.17±0.10(Predicted)
• Flash Point: 163.612oC
• PSA: 12.03000
• Density: 1.052g/cm3
• LogP: 3.46830
• Storage Temp.: Keep in dark place,Inert atmosphere,Room temperature
• Sensitive.: air sensitive
• XLogP3: 3.9
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 2
• Exact Mass: 183.104799419
• Heavy Atom Count: 14
• Complexity: 161

Purity/Quality:

97% ^*data from raw suppliers

N-Methylbiphenyl-2-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CNC1=CC=CC=C1C2=CC=CC=C2

Technology Process of N-methylbiphenyl-2-amine

There total 41 articles about N-methylbiphenyl-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

2-chloro-1,1'-biphenyl (2051-60-7,108321-69-3) + methylamine hydrochloride (593-51-1) → 2-(N-methylamino)-1,1'-biphenyl (14925-09-8)

Guidance literature:

With (R)-(-)-1-[(S_P)-2-(dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine; bis(tri-ortho-tolylphosphine)palladium⁽⁰⁾; sodium t-butanolate; In 1,4-dioxane; at 100 ℃; for 12h; Inert atmosphere; Glovebox;

DOI:10.1021/ol501739g

Reference yield: 99.0%

2-Bromobiphenyl (2052-07-5) + methylamine hydrochloride (593-51-1) → 2-(N-methylamino)-1,1'-biphenyl (14925-09-8)

Guidance literature:

With (R)-(-)-1-[(S_P)-2-(dicyclohexylphosphino)ferrocenyl]ethyldi-tert-butylphosphine; bis(tri-ortho-tolylphosphine)palladium⁽⁰⁾; sodium t-butanolate; In 1,4-dioxane; at 100 ℃; for 12h; Inert atmosphere; Glovebox;

DOI:10.1021/ol501739g

Reference yield: 89.0%

ethyl ((1,1’-biphenyl)-2-yl)carbamate (6301-18-4) → 2-(N-methylamino)-1,1'-biphenyl (14925-09-8)

Guidance literature:

With sodium bis(2-methoxyethoxy)aluminium dihydride; In tetrahydrofuran; at 50 ℃; for 6h;

DOI:10.1016/j.bmcl.2007.07.078

upstream raw materials:

2-Benzylpyridine

2-(N-benzoyl-N-methylamino)benzoic acid

1-Methyl-2-benzylpyridinium iodide

Dimethylammonium sulphite

Downstream raw materials:

phenanthridine

N-methylcarbazole

9H-carbazole

N-([1,1'-biphenyl]-2-yl)-2-chloro-N-methylacetamide