Benzamide, 2-ethyl-N,N-bis(1-methylethyl)-

Base Information

• Chemical Name: Benzamide, 2-ethyl-N,N-bis(1-methylethyl)-
• CAS No.: 153184-10-2
• Molecular Formula: C15H23NO
• Molecular Weight: 233.354
• DSSTox Substance ID: DTXSID30472216
• Nikkaji Number: J820.342C
• Wikidata: Q82301028
• Mol file: 153184-10-2.mol

Synonyms:Benzamide, 2-ethyl-N,N-bis(1-methylethyl)-;153184-10-2;N,N-dii-propyl-o-ethylbenzamide;DTXSID30472216

Chemical Property of Benzamide, 2-ethyl-N,N-bis(1-methylethyl)-

Chemical Property:

• Boiling Point: 353.0±21.0 °C(Predicted)
• PSA: 20.31000
• Density: 0.955±0.06 g/cm3(Predicted)
• LogP: 3.50800
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 1
• Rotatable Bond Count: 4
• Exact Mass: 233.177964357
• Heavy Atom Count: 17
• Complexity: 239

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCC1=CC=CC=C1C(=O)N(C(C)C)C(C)C

Technology Process of Benzamide, 2-ethyl-N,N-bis(1-methylethyl)-

There total 6 articles about Benzamide, 2-ethyl-N,N-bis(1-methylethyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

N,N-diisopropyl benzamide (20383-28-2) + ethyl iodide (75-03-6) → 2-ethyl-N,N-diisopropylbenzenecarboxamide (153184-10-2)

Guidance literature:

N,N-diisopropyl benzamide; With sec.-butyllithium; In tetrahydrofuran; cyclohexane; at -78 ℃; for 1h;

ethyl iodide; In tetrahydrofuran; cyclohexane; at -78 - 20 ℃; Further stages.;

DOI:10.1021/jo0007074

Reference yield: 70.0%

N,N-diisopropyl-2-methylbenzenecarboxamide (6641-72-1) + methyl iodide (74-88-4) → 2-ethyl-N,N-diisopropylbenzenecarboxamide (153184-10-2)

Guidance literature:

N,N-diisopropyl-2-methylbenzenecarboxamide; With choline chloride; glycerol; at 20 ℃; for 0.0833333h;

With tert.-butyl lithium; at 20 ℃; for 0.000555556h;

methyl iodide; at 20 ℃; Reagent/catalyst; regioselective reaction;

DOI:10.1039/d0cc00593b

Reference yield: 62.0%

N,N-diisopropyl-2-methylbenzenecarboxamide (6641-72-1) + methyl iodide (74-88-4) → 2-ethyl-N,N-diisopropylbenzenecarboxamide (153184-10-2) + N,N-bis(1-methylethyl)-2-(1-methylethyl)benzamide (153184-04-4)

Guidance literature:

N,N-diisopropyl-2-methylbenzenecarboxamide; With choline chloride; glycerol; at 20 ℃; for 0.0833333h;

With tert.-butyl lithium; at 20 ℃; for 0.000555556h;

methyl iodide; at 20 ℃; Reagent/catalyst; Temperature; regioselective reaction;

DOI:10.1039/d0cc00593b

upstream raw materials:

N,N-diisopropyl benzamide

ethyl iodide

benzoyl chloride

diisopropylamine

Downstream raw materials:

(S)-N,N-diisopropyl-2-(1-trimethylsilylethyl)benzamide