methyl 2-(acetylamino)-5-hydroxybenzoate

Base Information

Chemical Name:methyl 2-(acetylamino)-5-hydroxybenzoate
CAS No.:154664-44-5
Molecular Formula:C10H11NO4
Molecular Weight:209.202
Hs Code.:
Mol file:154664-44-5.mol

Synonyms:methyl 2-acetamido-5-hydroxybenzoate;2-ACETAMIDO-5-HYDROXYBENZOIC ACID METHYL ESTER;

Suppliers and Price of methyl 2-(acetylamino)-5-hydroxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

American Custom Chemicals Corporation
2-ACETAMIDO-5-HYDROXYBENZOIC ACID METHYL ESTER 95.00%
5MG
$ 496.85

Total 1 raw suppliers

Chemical Property of methyl 2-(acetylamino)-5-hydroxybenzoate

Chemical Property:

PSA：75.63000
LogP:1.21020

Purity/Quality:: 2-ACETAMIDO-5-HYDROXYBENZOIC ACID METHYL ESTER 95.00% ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of methyl 2-(acetylamino)-5-hydroxybenzoate

There total 3 articles about methyl 2-(acetylamino)-5-hydroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 1882-72-0
methyl 2-amino-5-hydroxybenzoate

: 108-24-7
acetic anhydride

: 154664-44-5
2-acetylamino-5-hydroxybenzoic acid methyl ester

Guidance literature:: In ethanol; at 40 - 50 ℃; for 3h;
DOI:10.1021/jo001696h

Reference yield: 69.0%

: 394-31-0
2-amino-5-hydroxybenzoic acid

: 124-41-4
sodium methylate

: 108-24-7
acetic anhydride

: 154664-44-5
2-acetylamino-5-hydroxybenzoic acid methyl ester

Guidance literature:: 2-amino-5-hydroxybenzoic acid; acetic anhydride; at 140 ℃; for 0.666667h;

sodium methylate; In methanol; at 20 ℃;

Reference yield:

: 394-31-0
2-amino-5-hydroxybenzoic acid

: 154664-44-5
2-acetylamino-5-hydroxybenzoic acid methyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: SOCl₂ / -20 - 20 °C

2: 50 °C

With thionyl chloride;
DOI:10.1016/j.bmcl.2006.10.033