2-(AcetylaMino)-5-(phenylMethoxy)-benzoic Acid Methyl Ester

Base Information

• Chemical Name: 2-(AcetylaMino)-5-(phenylMethoxy)-benzoic Acid Methyl Ester
• CAS No.: 340291-79-4
• Molecular Formula: C17H17NO4
• Molecular Weight: 299.326
• Mol file: 340291-79-4.mol

Synonyms:2-(AcetylaMino)-5-(phenylMethoxy)-benzoic Acid Methyl Ester

Chemical Property of 2-(AcetylaMino)-5-(phenylMethoxy)-benzoic Acid Methyl Ester

Chemical Property:

• Boiling Point: 513.3±45.0 °C(Predicted)
• PKA: 13.93±0.70(Predicted)
• PSA: 68.12000
• Density: 1 +-.0.06 g/cm3(Predicted)
• LogP: 3.66010
• Solubility.: Acetone, Dimethyl Sulfoxide, Methanol

Purity/Quality:

97% ^*data from raw suppliers

2-(Acetylamino)-5-(phenylmethoxy)-benzoicAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(AcetylaMino)-5-(phenylMethoxy)-benzoic Acid Methyl Ester

There total 3 articles about 2-(AcetylaMino)-5-(phenylMethoxy)-benzoic Acid Methyl Ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

benzyl bromide (100-39-0) + 2-acetylamino-5-hydroxybenzoic acid methyl ester (154664-44-5) → 2-acetylamino-5-benzyloxybenzoic acid methyl ester (340291-79-4)

Guidance literature:

With potassium carbonate; In acetone; for 3.5h; Heating;

DOI:10.1021/jo001696h

Reference yield:

2-amino-5-hydroxybenzoic acid (394-31-0) → 2-acetylamino-5-benzyloxybenzoic acid methyl ester (340291-79-4)

Guidance literature:

Multi-step reaction with 3 steps

1: SOCl₂ / -20 - 20 °C

2: 50 °C

3: acetone / 4 h

With thionyl chloride; In acetone;

DOI:10.1016/j.bmcl.2006.10.033

Reference yield:

methyl 2-amino-5-hydroxybenzoate (1882-72-0) → 2-acetylamino-5-benzyloxybenzoic acid methyl ester (340291-79-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 50 °C

2: acetone / 4 h

In acetone;

DOI:10.1016/j.bmcl.2006.10.033

upstream raw materials:

benzyl bromide

2-acetylamino-5-hydroxybenzoic acid methyl ester

2-amino-5-hydroxybenzoic acid

methyl 2-amino-5-hydroxybenzoate

Downstream raw materials:

2-amino-5-(benzyloxy)benzoic acid

2-amino-5-(benzyloxy)benzamide

5-benzyloxy-2-[2-(4-benzyl-piperidin-1-yl)-2-oxo-acetylamino]-benzamide

2-amino-5-benzyloxybenzoic acid methyl ester

Post a RFQ

Cas No.:

Product Name:

Quantity:

Please select Metric Ton KG G Pound L ML

Email:

Company name:

Valid Period:

Detailed Requirements:

• Sample
• MOQ
• GMP
• FDA
• Price
  FOB CIF CFR EXW
• Urgent purchase

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

Remove

Submit

1

What can I do for you?
Get Best Price

Get Best Price for 340291-79-4 2-(AcetylaMino)-5-(phenylMethoxy)-benzoic Acid Methyl Ester

Send

Send

Metric Ton KG G Pound L ML

Send

Send