7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole

Base Information

Chemical Name:7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole
CAS No.:155095-10-6
Molecular Formula:C17H22N2
Molecular Weight:254.375
Hs Code.:
Mol file:155095-10-6.mol

Synonyms:(4R,7S)-3-phenyl-4-methyl-7-isopropyl-4,5,6,7-tetrahydro-1H-indazole;3-phenyl-(4R,7S)-4-methyl-7-isopropyl-4,5,6,7-tetrahydroindazole;3-Phenyl-l-mentopyrazole;

Suppliers and Price of 7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole

Chemical Property:

PSA：28.68000
LogP:4.71360

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole

There total 8 articles about 7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 155095-12-8
(3R,6S)-2-Benzoyl-3-methyl-6-isopropylcyclohexanone

: 155095-10-6
(4R,7S)-3-phenyl-4-methyl-7-isopropyl-4,5,6,7-tetrahydro-1H-indazole

Guidance literature:: With hydrogenchloride; hydrazine hydrate;
DOI:10.1016/S0040-4039(00)61417-X

Reference yield: 78.0%

: 67-56-1
methanol

: 1314042-77-7
(4R,7S)-1-[{(2'S)-(1'-benzyloxycarbonyl)aziridin-2'-yl}carbonyl]-7-isopropyl-4-methyl-3-phenyl-4,5,6,7-tetrahydro-1H-indazole

: 104597-98-0
(S)-2-methoxycarbonyl-1-benzyloxycarbonylaziridine

: 155095-10-6
(4R,7S)-3-phenyl-4-methyl-7-isopropyl-4,5,6,7-tetrahydro-1H-indazole

Guidance literature:: With dmap; at 20 ℃; for 5h; Inert atmosphere;
DOI:10.1021/jo2010632

Reference yield:

: 98-88-4
benzoyl chloride

: 155095-10-6
(4R,7S)-3-phenyl-4-methyl-7-isopropyl-4,5,6,7-tetrahydro-1H-indazole

Guidance literature:: Multi-step reaction with 2 steps

1: 68 percent / LDA / tetrahydrofuran / 1.) -78 deg C, 30 min, 2.) r.t., 1.5 h

2: 96 percent / NH₂NH₂*H₂O, conc. aq. HCl / methanol / 16 h / Heating

With hydrogenchloride; hydrazine hydrate; lithium diisopropyl amide; In tetrahydrofuran; methanol;
DOI:10.1021/jo00104a045