2H-Imidazole-2-selone, 1,3-dihydro-1-methyl-

Base Information

Chemical Name:2H-Imidazole-2-selone, 1,3-dihydro-1-methyl-
CAS No.:157997-38-1
Molecular Formula:C4H6N2Se
Molecular Weight:161.065
Hs Code.:
Mol file:157997-38-1.mol

Synonyms:1-Methyl-1,3-dihydro-imidazole-2-selone;selenomethimazole;1,3-Dihydro-1-methyl-2H-imidazole-2-selone;MeSeI;(seim(Me)H;1-methylimidazole-2-selone;

Suppliers and Price of 2H-Imidazole-2-selone, 1,3-dihydro-1-methyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
1,3-Dihydro-1-methyl-2H-imidazole-2-selone
1g
$ 2475.00

Total 0 raw suppliers

Chemical Property of 2H-Imidazole-2-selone, 1,3-dihydro-1-methyl-

Chemical Property:

PSA：20.72000
LogP:0.16620

Purity/Quality:: 1,3-Dihydro-1-methyl-2H-imidazole-2-selone ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses 1,3-Dihydro-1-methyl-2H-imidazole-2-selone is a selenium analog which inhibits lactoperoxidase (LPO) as a treatment of hyperthyroidism. Also, it is derived from 1-Methylimidazole (M312980), which is a metabolite of 1-Methyl-2-thioimidazole (methimazole) and it inhibits bone resorption.

Technology Process of 2H-Imidazole-2-selone, 1,3-dihydro-1-methyl-

There total 2 articles about 2H-Imidazole-2-selone, 1,3-dihydro-1-methyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 678996-64-0
2,2'-bis(1-methylimidazolyl)diselenide

: 157997-38-1
1,3-Dihydro-1-methyl-2H-imidazole-2-selone

Guidance literature:: With sodium tetrahydroborate; In water; for 5h;
DOI:10.1021/ja063168e

Reference yield: 58.0%

: 616-47-7
1-methyl-1H-imidazole

: 157997-38-1
1,3-Dihydro-1-methyl-2H-imidazole-2-selone

Guidance literature:: With selenium; n-butyllithium; In tetrahydrofuran; hexane; 1.) -78 deg C, 35 min, -78 deg C to r.t., 2.) r.t., overnight;
DOI:10.1021/jo00095a056

Reference yield: 63.0%

: 7782-49-2
selenium

: 15529-49-4,41756-81-4
tris(triphenylphosphine)ruthenium(II) chloride

: 75-09-2
dichloromethane

: 157997-38-1
1,3-Dihydro-1-methyl-2H-imidazole-2-selone

: [Ru(selenomethimazolyl)2(PPh₃)2]

: [RuCl2(PPh3)(κ3-Se,N,N'-Se(selenomethimazolyl)2)]*CH2Cl2

Guidance literature:: With Na₂CO₃; In dichloromethane; the complex, selenomethimazole, Na2CO3 and Se were stirred anaerobicallyin CH2Cl2 for 48 h; filtered through diatomaceous earth, concd., layered with light petroleum, cooled to -20°C overnight; elem. anal.;
DOI:10.1021/om0608511