(3,5-Dichloropyridin-4-YL)methanol

Base Information

Chemical Name:(3,5-Dichloropyridin-4-YL)methanol
CAS No.:159783-46-7
Molecular Formula:C6H5Cl2NO
Molecular Weight:178.01600
Hs Code.:2933399090
DSSTox Substance ID:DTXSID70591298
Nikkaji Number:J2.703.092K
Wikidata:Q82485045
Mol file:159783-46-7.mol

Synonyms:(3,5-DICHLOROPYRIDIN-4-YL)METHANOL;159783-46-7;(3,5-Dichloro-4-pyridyl)methanol;4-Pyridinemethanol, 3,5-dichloro-;(3,5-Dichloro-pyridin-4-yl)-methanol;SCHEMBL321133;RARECHEM AL BD 0919;3,5-dichloro-4-Pyridinemethanol;DTXSID70591298;PWGOKQLNXKOIHM-UHFFFAOYSA-N;3,5-Dichloro4-hydroxymethylpyridine;AB9066;MFCD06202840;3,5-Dichloro-4-hydroxymethylpyridine;3.5-Dichloro-4-hydroxymethylpyridine;4-hydroxymethyl-3,5-dichloropyridine;(3,5-dichloropyridin-4-yl)-methanol;AKOS006291938;3,5-Dichloro-4-hydroxymethyl-pyridine;SB52762;(3.5-dichloro-pyridin-4-yl)-methanol;BS-21608;DB-064308;CS-0195175;EN300-1966933;A883279

Suppliers and Price of (3,5-Dichloropyridin-4-YL)methanol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(3,5-Dichloropyridin-4-yl)methanol
50mg
$ 45.00

Matrix Scientific
(3,5-Dichloro-4-pyridyl)methanol 98%
5g
$ 1544.00

Matrix Scientific
(3,5-Dichloro-4-pyridyl)methanol 98%
1g
$ 420.00

Matrix Scientific
(3,5-Dichloro-4-pyridyl)methanol 98%
500mg
$ 269.00

Frontier Specialty Chemicals
(3,5-Dichloropyridin-4-yl)methanol
1g
$ 80.00

Frontier Specialty Chemicals
(3,5-Dichloropyridin-4-yl)methanol
5g
$ 280.00

Crysdot
(3,5-Dichloropyridin-4-yl)methanol 95+%
5g
$ 813.00

AOBChem
(3,5-Dichloropyridin-4-yl)methanol 97%
5g
$ 491.00

AOBChem
(3,5-Dichloropyridin-4-yl)methanol 97%
10g
$ 836.00

AOBChem
(3,5-Dichloropyridin-4-yl)methanol 97%
100g
$ 4543.00

Total 12 raw suppliers

Chemical Property of (3,5-Dichloropyridin-4-YL)methanol

Chemical Property:

Boiling Point:280.2±35.0 °C(Predicted)
PKA:12.09±0.10(Predicted)
PSA：33.12000
Density:1.478±0.06 g/cm3(Predicted)
LogP:1.88070
XLogP3:1.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:2
Rotatable Bond Count:1
Exact Mass:176.9748192
Heavy Atom Count:10
Complexity:102

Purity/Quality:

97% ^*data from raw suppliers

(3,5-Dichloropyridin-4-yl)methanol ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=C(C(=C(C=N1)Cl)CO)Cl

Technology Process of (3,5-Dichloropyridin-4-YL)methanol

There total 4 articles about (3,5-Dichloropyridin-4-YL)methanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 136590-83-5
3,5-dichloropyridine-4-carboxaldehyde

: 159783-46-7
3,5-dichloro-4-hydroxymethylpyridine

Guidance literature:: With sodium tetrahydroborate; In methanol; at 0 ℃;
DOI:10.1002/cmdc.201600491

Reference yield:

: 144-55-8
sodium hydrogencarbonate

: 136590-83-5
3,5-dichloropyridine-4-carboxaldehyde

: 159783-46-7
3,5-dichloro-4-hydroxymethylpyridine

Guidance literature:: With hydrogenchloride; sodium borohydrid; In ethanol;

Reference yield:

: 2457-47-8
3,5-dichloropyridine

: 159783-46-7
3,5-dichloro-4-hydroxymethylpyridine

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran / -78 °C

1.2: -78 °C

2.1: sodium tetrahydroborate / ethanol / 0 °C

With sodium tetrahydroborate; lithium diisopropyl amide; In tetrahydrofuran; ethanol;
DOI:10.1039/d0cp06612e