Methyl 3-methoxy-4-(phenylmethoxy)benzenepropanoate

Base Information

Chemical Name:Methyl 3-methoxy-4-(phenylmethoxy)benzenepropanoate
CAS No.:1700-32-9
Molecular Formula:C18H20O4
Molecular Weight:300.354
Hs Code.:
DSSTox Substance ID:DTXSID601221489

Synonyms:DTXSID601221489;1700-32-9;Methyl 3-methoxy-4-(phenylmethoxy)benzenepropanoate

Suppliers and Price of Methyl 3-methoxy-4-(phenylmethoxy)benzenepropanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 3-methoxy-4-(phenylmethoxy)benzenepropanoate

Chemical Property:

XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:8
Exact Mass:300.13615911
Heavy Atom Count:22
Complexity:325

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C(C=CC(=C1)CCC(=O)OC)OCC2=CC=CC=C2

Technology Process of Methyl 3-methoxy-4-(phenylmethoxy)benzenepropanoate

There total 6 articles about Methyl 3-methoxy-4-(phenylmethoxy)benzenepropanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

: 56024-44-3
methyl 3-(4-hydroxy-3-methoxyphenyl)propanoate

: 100-39-0
benzyl bromide

: 1700-32-9
methyl 4-benzyloxy-3-methoxybenzenepropanoate

Guidance literature:: With tetra-(n-butyl)ammonium iodide; sodium hydride; In tetrahydrofuran; for 13h; Ambient temperature;

Reference yield:

: 67-56-1
methanol

: 30034-49-2
β-(4-benzyloxy-3-methoxyphenyl)propionic acid

: 1700-32-9
methyl 4-benzyloxy-3-methoxybenzenepropanoate

Guidance literature:: hydrogenchloride; In acetic acid methyl ester; for 6h; Heating / reflux;

Reference yield:

: 1135-24-6,537-98-4
(E)-3-(4-hydroxy-3-methoxyphenyl)acrylic acid

: 1700-32-9
methyl 4-benzyloxy-3-methoxybenzenepropanoate

Guidance literature:: Multi-step reaction with 3 steps

1: 98 percent / H₂, NaOH / 10percent Pd/C / H₂O / 12 h / 22501.8 Torr

2: 98 percent / conc.H₂SO₄ / Heating

3: 1) NaH, 2) tetrabutylammonium iodide / 1) THF, 0 deg C, 0.5 h, 2) 0 deg C

With sodium hydroxide; sulfuric acid; hydrogen; tetra-(n-butyl)ammonium iodide; sodium hydride; palladium on activated charcoal; In water;
DOI:10.1021/jo00060a038