L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-3-formyl-

Base Information

Chemical Name:L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-3-formyl-
CAS No.:186689-03-2
Molecular Formula:C15H19NO6
Molecular Weight:309.319
Hs Code.:
DSSTox Substance ID:DTXSID70444159
Nikkaji Number:J830.049F
Wikidata:Q82262196

Synonyms:186689-03-2;L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-3-formyl-;boc-3-formyl-l-tyrosine;SCHEMBL2630631;DTXSID70444159;N-BOC-3-FORMYL-L-TYROSINE;AT18680;N-(tert-Butoxycarbonyl)-3-formyl-L-tyrosine;EN300-746788;Z1508686697;(2S)-2-{[(tert-butoxy)carbonyl]amino}-3-(3-formyl-4-hydroxyphenyl)propanoic acid

Suppliers and Price of L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-3-formyl-

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-3-formyl-

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:3
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:7
Exact Mass:309.12123733
Heavy Atom Count:22
Complexity:417

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(C)(C)OC(=O)NC(CC1=CC(=C(C=C1)O)C=O)C(=O)O
Isomeric SMILES:CC(C)(C)OC(=O)N[C@@H](CC1=CC(=C(C=C1)O)C=O)C(=O)O

Technology Process of L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-3-formyl-

There total 5 articles about L-Tyrosine, N-[(1,1-dimethylethoxy)carbonyl]-3-formyl- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 64.0%

: 67-66-3,8013-54-5
chloroform

: 3978-80-1
Boc-Tyr-OH

: 186689-03-2
2-(tert-butoxycarbonylamino)-3-(3-formyl-4-hydroxyphenyl)propanoic acid

Guidance literature:: With sodium hydroxide; In water; for 4h; Reflux;
DOI:10.14233/ajchem.2013.14893

Reference yield:

: 60-18-4,18875-48-4,25619-78-7,30704-25-7
L-tyrosine

: 186689-03-2
2-(tert-butoxycarbonylamino)-3-(3-formyl-4-hydroxyphenyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

2: NaOH / H₂O

With sodium hydroxide; In water;
DOI:10.1021/jo9902751

Reference yield:

: 24424-99-5
di-tert-butyl dicarbonate

: 186689-03-2
2-(tert-butoxycarbonylamino)-3-(3-formyl-4-hydroxyphenyl)propanoic acid

Guidance literature:: Multi-step reaction with 2 steps

1: 92 percent / Et₃N / dioxane; H₂O / 18 h / Ambient temperature

2: 66 percent Turnov_. / NaOH / H₂O / 6.5 h

With sodium hydroxide; triethylamine; In 1,4-dioxane; water;
DOI:10.1021/jo962099r