Methyl 4-(4-hydroxy-2-methylphenyl)butanoate

Base Information

• Chemical Name: Methyl 4-(4-hydroxy-2-methylphenyl)butanoate
• CAS No.: 19143-96-5
• Molecular Formula: C₁₂H₁₆O₃
• Molecular Weight: 208.257
• DSSTox Substance ID: DTXSID60533046
• Wikidata: Q82406098
• Mol file: 19143-96-5.mol

Synonyms:METHYL 4-(4-HYDROXY-2-METHYLPHENYL)BUTANOATE;19143-96-5;DTXSID60533046

Chemical Property of Methyl 4-(4-hydroxy-2-methylphenyl)butanoate

Chemical Property:

• XLogP3: 2.4
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 5
• Exact Mass: 208.109944368
• Heavy Atom Count: 15
• Complexity: 203

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=C(C=CC(=C1)O)CCCC(=O)OC

Technology Process of Methyl 4-(4-hydroxy-2-methylphenyl)butanoate

There total 3 articles about Methyl 4-(4-hydroxy-2-methylphenyl)butanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

γ-(2-methyl-4-methoxyphenyl)butyric acid (6307-30-8) → γ-(4-Hydroxy-2-methyl-phenyl)-buttersaeure-methylester (19143-96-5)

Guidance literature:

Multi-step reaction with 2 steps

1: aq. HI / Heating

2: ion-exchange resin + form> / Heating

With ion-exchange resin + form>; hydrogen iodide;

DOI:10.1007/BF00913783

Reference yield:

methanol (67-56-1) + 4-(4-hydroxy-2-methylphenyl)butanoic acid (19143-95-4) → γ-(4-Hydroxy-2-methyl-phenyl)-buttersaeure-methylester (19143-96-5)

Guidance literature:

With ion-exchange resin + form>; Heating;

DOI:10.1007/BF00913783

Reference yield:

→ γ-(4-Hydroxy-2-methyl-phenyl)-buttersaeure-methylester (19143-96-5)

Guidance literature:

IXb;

upstream raw materials:

methanol

4-(4-hydroxy-2-methylphenyl)butanoic acid

γ-(2-methyl-4-methoxyphenyl)butyric acid

Downstream raw materials:

3-Hydroxy-2-[2-(4-hydroxy-2-methyl-phenyl)-ethyl]-3-methyl-butyric acid methyl ester

2-[2-(4-Hydroxy-2-methyl-phenyl)-ethyl]-3-methyl-butane-1,3-diol

4-(3-Hydroxymethyl-4-methyl-pent-4-enyl)-3-methyl-phenol

2-[2-(4-Hydroxy-2-methyl-phenyl)-ethyl]-3-methyl-but-3-enoic acid methyl ester