1S,2S-N,N'-bis(phenylMethyl)-1,2-CyclohexanediaMine

Base Information

• Chemical Name: 1S,2S-N,N'-bis(phenylMethyl)-1,2-CyclohexanediaMine
• CAS No.: 191480-61-2
• Molecular Formula: C20H26N2
• Molecular Weight: 294.43
• Mol file: 191480-61-2.mol

Synonyms:

Chemical Property of 1S,2S-N,N'-bis(phenylMethyl)-1,2-CyclohexanediaMine

Chemical Property:

• Boiling Point: 436.3±40.0 °C(Predicted)
• PKA: 9.85±0.40(Predicted)
• Density: 1.05±0.1 g/cm3(Predicted)

Purity/Quality:

97% ^*data from raw suppliers

(1S,2S)-N1,N2-Dibenzylcyclohexane-1,2-diamine 97% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1S,2S-N,N'-bis(phenylMethyl)-1,2-CyclohexanediaMine

There total 70 articles about 1S,2S-N,N'-bis(phenylMethyl)-1,2-CyclohexanediaMine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(1R,2R)-1,2-diaminocyclohexane (20439-47-8) + benzaldehyde (100-52-7) → (1R,2R)-N,N'-dibenzylcyclohexane-1,2-diamine (65838-10-0,135613-88-6,143443-23-6,191480-61-2)

Guidance literature:

(1R,2R)-1,2-diaminocyclohexane; benzaldehyde; In methanol; for 0.5h; Heating;

With sodium tetrahydroborate; In methanol; for 0.25h; Heating;

DOI:10.1016/S0040-4039(01)02054-8

Reference yield: 99.0%

(R,R)-N,N′-bis(phenylmethylene)-1,2-cyclohexanediamine (3187-82-4,65838-45-1,113282-15-8,135682-70-1,147127-11-5,133695-15-5) → (1R,2R)-N,N'-dibenzylcyclohexane-1,2-diamine (65838-10-0,135613-88-6,143443-23-6,191480-61-2)

Guidance literature:

With sodium tetrahydroborate;

DOI:10.1016/j.tetasy.2017.09.014

Reference yield: 98.0%

7-Benzyl-7-aza-bicyclo[4.1.0]heptane (24417-01-4) + benzylamine (100-46-9) → N,N′-dibenzyl-(±)-trans-1,2-diaminocyclohexane (65838-10-0,135613-88-6,143443-23-6,191480-61-2)

Guidance literature:

With tris(pentafluorophenyl)borate; In acetonitrile; at 65 ℃; for 16h;

DOI:10.1021/jo0343578

upstream raw materials:

N,N'-(cyclohexane-1,2-diyl)bis(1-phenylmethanimine)

N,N'-bisbenzylidene-1,3-diaminopropane

1,3-dibenzyl-2-phenylimidazolidine

N,N'-dibenzyl-1,3-diaminopropane

Downstream raw materials:

(1R,2R)-N,N'-dibenzyl-N,N'-bis(ethan-(1-(S)-methyl)-1-ol)-trans-diaminocyclohexane

(1R,2R)-N,N'-dibenzylcyclohexane-1,2-diamine

1,3-dibenzyl perhydrobenzimidazolinium chloride

(R,S)-(3al,7al,1'lu)-1,3-dibenzyloctahydro-2-(4'-methyl-1',2'-pentadienyl)-1H-1,3,2-benzodiazaphosphole 2-oxide