3,5-Diphenyl-1,3,4-oxadiazol-2(3H)-one

Base Information

Chemical Name:3,5-Diphenyl-1,3,4-oxadiazol-2(3H)-one
CAS No.:19226-10-9
Molecular Formula:C14H10N2O2
Molecular Weight:238.246
Hs Code.:2934999090
ChEMBL ID:CHEMBL3218786
DSSTox Substance ID:DTXSID90497086
Nikkaji Number:J99.867B
Mol file:19226-10-9.mol

Synonyms:3,5-Diphenyl-1,3,4-oxadiazol-2(3H)-one;19226-10-9;3,5-diphenyl-1,3,4-oxadiazol-2-one;CHEMBL3218786;SCHEMBL14007602;DTXSID90497086

Suppliers and Price of 3,5-Diphenyl-1,3,4-oxadiazol-2(3H)-one

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 3,5-Diphenyl-1,3,4-oxadiazol-2(3H)-one

Chemical Property:

PSA：48.03000
LogP:2.49250
XLogP3:3.2
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:238.074227566
Heavy Atom Count:18
Complexity:342

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NN(C(=O)O2)C3=CC=CC=C3

Technology Process of 3,5-Diphenyl-1,3,4-oxadiazol-2(3H)-one

There total 18 articles about 3,5-Diphenyl-1,3,4-oxadiazol-2(3H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 89.0%

: 124-38-9,18923-20-1
carbon dioxide

: 15424-14-3
N-phenylbenzohydrazonoyl chloride

: 19226-10-9
5-phenyl-3-phenyl-1,3,4-oxadiazol-2(3H)-one

Guidance literature:: With 18-crown-6 ether; cesium fluoride; In toluene; at 25 ℃; for 12h; under 15001.5 Torr; Reagent/catalyst; Solvent; Concentration; Schlenk technique; Autoclave;
DOI:10.1021/acs.joc.7b00963

Reference yield: 87.0%

: 1199-02-6
5-phenyl-3H-[1,3,4]oxadiazol-2-one

: 66003-76-7
Diphenyliodonium triflate

: 19226-10-9
5-phenyl-3-phenyl-1,3,4-oxadiazol-2(3H)-one

Guidance literature:: With copper(l) iodide; triethylamine; In 1,2-dichloro-ethane; at 60 ℃; for 24h; chemoselective reaction; Inert atmosphere;
DOI:10.1002/adsc.202100426

Reference yield: 84.0%

: 124-38-9,18923-20-1
carbon dioxide

: 100-52-7
benzaldehyde

: 100-63-0
phenylhydrazine

: 19226-10-9
5-phenyl-3-phenyl-1,3,4-oxadiazol-2(3H)-one

Guidance literature:: With tert.-butylhydroperoxide; potassium tert-butylate; potassium iodide; In water; N,N-dimethyl-formamide; at 80 ℃; for 8h; under 15001.5 Torr; Solvent; Reagent/catalyst; Temperature; Mechanism; Catalytic behavior; Autoclave;
DOI:10.1039/c9ob01200a