(2S)-2-Phenylhexane-2-ol

Base Information

Chemical Name:(2S)-2-Phenylhexane-2-ol
CAS No.:19641-54-4
Molecular Formula:C12H18O
Molecular Weight:178.274
Hs Code.:
DSSTox Substance ID:DTXSID001289524
Nikkaji Number:J2.455.056G

Synonyms:19641-54-4;(2S)-2-Phenylhexane-2-ol;DTXSID001289524;(alphaS)-alpha-Butyl-alpha-methylbenzenemethanol

Suppliers and Price of (2S)-2-Phenylhexane-2-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Chemical Property of (2S)-2-Phenylhexane-2-ol

Chemical Property:

XLogP3:3.1
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:4
Exact Mass:178.135765193
Heavy Atom Count:13
Complexity:138

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCCCC(C)(C1=CC=CC=C1)O
Isomeric SMILES:CCCC[C@@](C)(C1=CC=CC=C1)O

Technology Process of (2S)-2-Phenylhexane-2-ol

There total 10 articles about (2S)-2-Phenylhexane-2-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1009-14-9
phenyl butyl ketone

: 544-97-8
dimethyl zinc(II)

: 19641-54-4
(S)-2-phenyl-hexan-2-ol

: 73464-88-7
(R)-2-phenyl-hexan-2-ol

Guidance literature:: With titanium(IV) isopropylate; calcium hydride; (1S,2R,4S)-N-(naphth-1-ylmethyl)-2-hydroxy-7,7-dimethylbicyclo<2.2.1>hept-1-ylmethanesulfonamide; In toluene; at 4 ℃; for 408h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
DOI:10.1016/S0040-4020(98)00236-1

Reference yield:

: 191479-34-2
(+/-)-2-phenylhex-2-yl hydroperoxide

: 19641-54-4
(S)-2-phenyl-hexan-2-ol

: 73464-88-7
(R)-2-phenyl-hexan-2-ol

: (R)-2-Phenyl-hex-2-yl-hydroperoxide

: (S)-2-Phenyl-hex-2-yl-hydroperoxide

Guidance literature:: With (Rp)-xylyl-PHANEPHOS; In chloroform-d1; at -67 - 25 ℃; Title compound not separated from byproducts.;
DOI:10.1021/ja070482f

Reference yield:

: 591-78-6
n-hexan-2-one

: 16635-23-7
phenyltriisopropoxytitanium(IV)

: 19641-54-4
(S)-2-phenyl-hexan-2-ol

: 73464-88-7
(R)-2-phenyl-hexan-2-ol

Guidance literature:: phenyltriisopropoxytitanium(IV); With (1R,2R)-N,N'-bis-(2,3,4,5,6-pentafluorobenzenesulfonyl)-cyclohexane-1,2-diamine; magnesium bromide; In toluene; at 20 ℃; for 1h; Inert atmosphere;

n-hexan-2-one; In toluene; at 0 ℃; for 16h; Overall yield = 81 %; enantioselective reaction; Inert atmosphere;
DOI:10.1039/c5ra18871g