Hydroxylamine, O-[(1S)-1-phenylbutyl]-

Base Information

• Chemical Name: Hydroxylamine, O-[(1S)-1-phenylbutyl]-
• CAS No.: 197709-50-5
• Molecular Formula: C10H15NO
• Molecular Weight: 165.235
• DSSTox Substance ID: DTXSID70442357
• Nikkaji Number: J881.277B
• Wikidata: Q82259591
• Mol file: 197709-50-5.mol

Synonyms:Hydroxylamine, O-[(1S)-1-phenylbutyl]-;197709-50-5;DTXSID70442357;O-[(S)-alpha-Propylbenzyl]hydroxylamine

Chemical Property of Hydroxylamine, O-[(1S)-1-phenylbutyl]-

Chemical Property:

• XLogP3: 2.1
• Hydrogen Bond Donor Count: 1
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 4
• Exact Mass: 165.115364102
• Heavy Atom Count: 12
• Complexity: 110

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CCCC(C1=CC=CC=C1)ON
• Isomeric SMILES: CCC[C@@H](C1=CC=CC=C1)ON

Technology Process of Hydroxylamine, O-[(1S)-1-phenylbutyl]-

There total 2 articles about Hydroxylamine, O-[(1S)-1-phenylbutyl]- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

(S)-(-)-N-(1-phenylbutoxy)phthalimide (185758-21-8) → (S)-O-(1-phenylbutyl)hydroxylamine (197709-50-5)

Guidance literature:

With hydrazine hydrate; In ethanol; for 1h; Heating;

Reference yield:

(R)-1-butylphenylethanol (22144-60-1) → (S)-O-(1-phenylbutyl)hydroxylamine (197709-50-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Ph₃P, DEAD / tetrahydrofuran / 72 h / 50 °C

2: 78 percent / N₂H₄*H₂O / ethanol / 1 h / Heating

With hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol;

Reference yield: 94.0%

para-bromoacetophenone (99-90-1) + (S)-O-(1-phenylbutyl)hydroxylamine (197709-50-5) → (E)-(S)-(-)-O-(1-phenylbutyl) 4-bromoacetophenone oxime

Guidance literature:

In ethanol; at 20 ℃;

DOI:10.1039/b310624a

upstream raw materials:

(S)-(-)-N-(1-phenylbutoxy)phthalimide

(R)-1-butylphenylethanol

Downstream raw materials:

(S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime

(E)-(S)-(-)-O-(1-phenylbutyl) pivaldehyde oxime

(E)-(S)-(-)-O-(1-phenylbutyl) acetophenone oxime

(E)-(S)-(+)-O-(1-phenylbutyl) 2,2-dimethylbutyraldehyde oxime