(S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime

Base Information

• Chemical Name: (S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime
• CAS No.: 197709-52-7
• Molecular Formula: C₁₈H₂₁NO₂
• Molecular Weight: 283.37
• Mol file: 197709-52-7.mol

Synonyms:(S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime

Chemical Property of (S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime

There total 3 articles about (S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4-methoxy-benzaldehyde (123-11-5) + (S)-O-(1-phenylbutyl)hydroxylamine (197709-50-5) → (S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime (197709-52-7)

Guidance literature:

With pyridine; for 24h;

Reference yield:

(R)-1-butylphenylethanol (22144-60-1) → (S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime (197709-52-7)

Guidance literature:

Multi-step reaction with 3 steps

1: Ph₃P, DEAD / tetrahydrofuran / 72 h / 50 °C

2: 78 percent / N₂H₄*H₂O / ethanol / 1 h / Heating

3: 75 percent / pyridine / 24 h

With pyridine; hydrazine hydrate; triphenylphosphine; diethylazodicarboxylate; In tetrahydrofuran; ethanol;

Reference yield:

(S)-(-)-N-(1-phenylbutoxy)phthalimide (185758-21-8) → (S)-O-(1-Phenylbutyl)-p-anisaldehyde oxime (197709-52-7)

Guidance literature:

Multi-step reaction with 2 steps

1: 78 percent / N₂H₄*H₂O / ethanol / 1 h / Heating

2: 75 percent / pyridine / 24 h

With pyridine; hydrazine hydrate; In ethanol;

upstream raw materials:

4-methoxy-benzaldehyde

(S)-O-(1-phenylbutyl)hydroxylamine

(R)-1-butylphenylethanol

(S)-(-)-N-(1-phenylbutoxy)phthalimide

Downstream raw materials:

(S)-(-)-N-Benzyloxycarbonyl-1-(4-methoxyphenyl)but-3-enylamine

(1S)-1-(4-methoxyphenyl)but-3-en-1-amine

(S)-1-(4-Methoxyphenyl)-N-[(S)-1-phenylbutoxy]but-3-enylamine