Phosphinic chloride, bis(4-methoxyphenyl)-

Base Information

• Chemical Name: Phosphinic chloride, bis(4-methoxyphenyl)-
• CAS No.: 20434-06-4
• Molecular Formula: C14H14ClO3P
• Molecular Weight: 296.69
• DSSTox Substance ID: DTXSID50501512
• Nikkaji Number: J1.385.730J
• Mol file: 20434-06-4.mol

Synonyms:bis-p-methoxyphenylphosphinic chloride;di-p-anisylphosphinic chloride;

Chemical Property of Phosphinic chloride, bis(4-methoxyphenyl)-

Chemical Property:

• PSA: 45.34000
• LogP: 3.17150
• XLogP3: 3.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 296.0369090
• Heavy Atom Count: 19
• Complexity: 293

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COC1=CC=C(C=C1)P(=O)(C2=CC=C(C=C2)OC)Cl

Technology Process of Phosphinic chloride, bis(4-methoxyphenyl)-

There total 6 articles about Phosphinic chloride, bis(4-methoxyphenyl)- which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

bis(4-methoxyphenyl)phosphine oxide (15754-51-5) → bis(4-methoxyphenyl)phosphinic acid chloride (20434-06-4)

Guidance literature:

With thionyl chloride; In benzene; for 2h; Heating;

DOI:10.1021/ol035629w

Reference yield:

bis(4-methoxyphenyl)phosphinic acid (20434-05-3) → bis(4-methoxyphenyl)phosphinic acid chloride (20434-06-4)

Guidance literature:

With thionyl chloride;

DOI:10.1002/ardp.19683010707

Reference yield:

1-bromo-4-methoxy-benzene (104-92-7) → bis(4-methoxyphenyl)phosphinic acid chloride (20434-06-4)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) diethyl phosphate, Et₂O, (ii) Br₂

2: SOCl₂

With thionyl chloride;

DOI:10.1002/ardp.19683010707

upstream raw materials:

bis(4-methoxyphenyl)phosphinic acid

bis(4-methoxyphenyl)phosphine oxide

4-methoxyphenyl magnesium bromide

1-bromo-4-methoxy-benzene

Downstream raw materials:

Bis-(4-methoxy-phenyl)-phosphinsaeure-isocyanat

O-(bis-p-methoxyphenylphosphinyl)acetone oxime

1-(2-bromophenyl)ethenyl di(4-methoxyphenyl)phosphinate

1,1-dimethylethyl [[bis(4-methoxyphenyl)phosphinyl]oxy]carbamate