3-(DiMethylaMino)-1-(4-Methoxyphenyl)propan-1-one

Base Information

• Chemical Name: 3-(DiMethylaMino)-1-(4-Methoxyphenyl)propan-1-one
• CAS No.: 2138-33-2
• Molecular Formula: C12H17NO2
• Molecular Weight: 207.272
• Hs Code.: 2922509090
• Mol file: 2138-33-2.mol

Synonyms:1-(4-methoxyphenyl)-3-dimethylamino-1-propanone;3-(DIMETHYLAMINO)-1-(4-METHOXYPHENYL)-1-PROPANONE;β-dimethylaminopropiophenone;3-dimethylamino-1-(4-methoxy-phenyl)-propan-1-one;3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one hydrochloride;3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one;3-Dimethylamino-1-(4-methoxypphenyl)-propan-1-on;3-(N,N-dimethylamino)-1-(4-methoxyphenyl)propan-1-one;

Chemical Property of 3-(DiMethylaMino)-1-(4-Methoxyphenyl)propan-1-one

Chemical Property:

• Melting Point: 181 °C
• Boiling Point: 318.2±22.0 °C(Predicted)
• PKA: 8.71±0.28(Predicted)
• PSA: 29.54000
• Density: 1.027±0.06 g/cm3(Predicted)
• LogP: 1.82960

Purity/Quality:

97% ^*data from raw suppliers

3-(Dimethylamino)-1-(4-methoxyphenyl)propan-1-one ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 3-(DiMethylaMino)-1-(4-Methoxyphenyl)propan-1-one

There total 10 articles about 3-(DiMethylaMino)-1-(4-Methoxyphenyl)propan-1-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-dimethylamino-1-(4-methoxy-phenyl)-propan-1-one; hydrobromide (87142-65-2) → 3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one (2138-33-2)

Guidance literature:

With phosphate buffer; In chloroform; at 37 ℃; pH 7.4;

DOI:10.1002/jps.2600720812

Reference yield: 80.0%

→ 3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one (2138-33-2)

Guidance literature:

With hydrogenchloride; In ethanol; water; for 5h; Reflux;

Reference yield: 65.0%

3-dimethylamino-4'-methoxyacrylophenone (18096-70-3,78090-00-3) → 3-(dimethylamino)-1-(4-methoxyphenyl)propan-1-one (2138-33-2)

Guidance literature:

With lithium aluminium tetrahydride; In tetrahydrofuran;

DOI:10.1016/S0040-4020(01)85083-3

upstream raw materials:

formaldehyd

N,N-dimethylammonium chloride

1-(4-methoxyphenyl)ethanone

dimethyl amine

Downstream raw materials:

1-(4-methoxyphenyl)-3-morpholinopropan-1-one

[3-(4-methoxy-phenyl)-3-oxo-propyl]-trimethyl-ammonium; bromide

5-(4-methoxyphenyl)-5-oxopentanenitrile

3-dimethylamino-1-(4-hydroxy-phenyl)-propan-1-one