4-Pentynoic acid, methyl ester

Base Information

• Chemical Name: 4-Pentynoic acid, methyl ester
• CAS No.: 21565-82-2
• Molecular Formula: C6H8O2
• Molecular Weight: 112.128
• Hs Code.: 2916190090
• Mol file: 21565-82-2.mol

Synonyms:4-Pentynoic Acid Methyl Ester;METHYL PENT-4-YNOATE;

Chemical Property of 4-Pentynoic acid, methyl ester

Chemical Property:

• Vapor Pressure: 5.38mmHg at 25°C
• Boiling Point: 101-102 °C(Press: 175 Torr)
• PSA: 26.30000
• Density: 0.976±0.06 g/cm3(Predicted)
• LogP: 0.57280

Purity/Quality:

97% ^*data from raw suppliers

4-PentynoicAcidMethylEster ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 4-Pentynoic acid, methyl ester

There total 18 articles about 4-Pentynoic acid, methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

methanol (67-56-1) + 4-pentynoic acid (6089-09-4) → methyl pent-4-ynoate (21565-82-2)

Guidance literature:

With thionyl chloride; at 0 - 20 ℃;

Reference yield: 100.0%

trimethyl ortho-4-pentynoate (624728-36-5) → methyl pent-4-ynoate (21565-82-2)

Guidance literature:

With silica gel; In hexane; dichloromethane;

DOI:10.1081/SCC-120023984

Reference yield: 98.0%

4-pentynoic acid (6089-09-4) + acetyl chloride (75-36-5) → methyl pent-4-ynoate (21565-82-2)

Guidance literature:

In methanol;

upstream raw materials:

methanol

4-pentynoic acid

diazomethyl-trimethyl-silane

trimethyl ortho-4-pentynoate

Downstream raw materials:

5-(2,5-difluoro-3-nitro-phenyl)-pent-4-ynoic acid methyl ester

5-(2-fluoro-3-nitro-phenyl)-pent-4-ynoic acid methyl ester

5-(4-fluoro-3-nitro-phenyl)-pent-4-ynoic acid methyl ester

5-(3-fluoro-5-nitro-phenyl)-pent-4-ynoic acid methyl ester