2-ethoxymethyl-pyridine

Base Information

• Chemical Name: 2-ethoxymethyl-pyridine
• CAS No.: 21897-20-1
• Molecular Formula: C8H11NO
• Molecular Weight: 137.181
• Mol file: 21897-20-1.mol

Synonyms:picOEt;[Pyridyl-(2)-methyl]-ethyl-ether;2-(ethoxymethyl)pyridine;2-ethoxymethyl-pyridine;[Pyridyl-(2)-methyl]-aethyl-aether;2-Aethoxymethyl-pyridin;

Chemical Property of 2-ethoxymethyl-pyridine

Chemical Property:

• PSA: 22.12000
• LogP: 1.61810

Purity/Quality:

99% ^*data from raw suppliers

2-(ethoxymethyl)-Pyridine 97.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-ethoxymethyl-pyridine

There total 5 articles about 2-ethoxymethyl-pyridine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

2-methylpyridine N-oxide (931-19-1) + chloroformic acid ethyl ester (541-41-3) → 2-pyridylmethyl ethyl ether (21897-20-1) + ethyl 2-pyridylmethyl carbonate (130660-69-4)

Guidance literature:

With triethylamine; In ethanol; for 12h; Ambient temperature;

Reference yield: 7.0%

triazolopyridine (274-59-9) → 2-pyridylmethyl ethyl ether (21897-20-1) + (E)-1,2-bis(2-pyridyl)ethene (13341-40-7)

Guidance literature:

With palladium on activated charcoal; In ethanol; at 150 ℃; for 24h; Reagent/catalyst; Autoclave;

DOI:10.3998/ark.5550190.p008.227

Reference yield:

2-chloromethylpyridine (4377-33-7) + sodium ethanolate (141-52-6) → 2-pyridylmethyl ethyl ether (21897-20-1)

Guidance literature:

With ethanol;

upstream raw materials:

2-chloromethylpyridine

sodium ethanolate

2-methylpyridine N-oxide

chloroformic acid ethyl ester

Downstream raw materials:

2-[(ethoxy)(phenyl)methyl]pyridine

α-ethyl-α-phenyl-2-pyridinemethanol

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