1,3-Dimethoxy-2,2-bis(methoxymethyl)propane

Base Information

• Chemical Name: 1,3-Dimethoxy-2,2-bis(methoxymethyl)propane
• CAS No.: 2209-92-9
• Molecular Formula: C9H20O4
• Molecular Weight: 192.25300
• Hs Code.: 2909199090
• DSSTox Substance ID: DTXSID80550679
• Nikkaji Number: J46.172E
• Wikidata: Q63409605
• Mol file: 2209-92-9.mol

Synonyms:1,3-Dimethoxy-2,2-bis(methoxymethyl)propane;2209-92-9;Pentaerythrittetramethylether;Pentaerythrit-tetramethylester;SCHEMBL51026;DTXSID80550679;PENTAERYTHRO-TETRAMETHYL ETHER;AS-0223;Q63409605

Chemical Property of 1,3-Dimethoxy-2,2-bis(methoxymethyl)propane

Chemical Property:

• PSA: 36.92000
• LogP: 0.55840
• XLogP3: -0.2
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 8
• Exact Mass: 192.13615911
• Heavy Atom Count: 13
• Complexity: 86.7

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: COCC(COC)(COC)COC

Technology Process of 1,3-Dimethoxy-2,2-bis(methoxymethyl)propane

There total 6 articles about 1,3-Dimethoxy-2,2-bis(methoxymethyl)propane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

trimethyl phosphite (512-56-1) + Pentaerythritol (115-77-5) → tetramethyl pentaerythritol (2209-92-9)

Guidance literature:

With iron(II) triflate; In neat (no solvent); at 100 ℃;

DOI:10.1002/cssc.201701841

Reference yield: 65.0%

4,4-bis(hydroxymethyl)-2,6-dioxaheptane (55502-63-1) + methyl iodide (74-88-4) → tetramethyl pentaerythritol (2209-92-9)

Guidance literature:

4,4-bis(hydroxymethyl)-2,6-dioxaheptane; With sodium hydride; In tetrahydrofuran; for 1h; Reflux;

methyl iodide; In tetrahydrofuran; at 10 - 20 ℃; for 4h; Reflux;

Reference yield:

methanol (67-56-1) + pentaerythritol tetrabromide (3229-00-3) → tetramethyl pentaerythritol (2209-92-9)

Guidance literature:

With potassium hydroxide; at 120 - 150 ℃;

upstream raw materials:

methanol

pentaerythritol tetrabromide

sodium methylate

Pentaerythritol